Metagenomic and metabolomic analyses reveal synergistic effects of fecal microbiota transplantation and anti-PD-1 therapy on treating colorectal cancer.

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第一作者： Jiayuan,Huang

第一单位： School of Medicine, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, China.

作者： Jiayuan,Huang ^[1] ; Xing,Zheng ^[2] ; Wanying,Kang ^[1] ; Huaijie,Hao ^[2] ; Yudan,Mao ^[1] ; Hua,Zhang ^[3] ; Yuan,Chen ^[1] ; Yan,Tan ^[2] ; Yulong,He ^[1] ; Wenjing,Zhao ^[3] ; Yiming,Yin ^[1]

作者单位： School of Medicine, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, China. ^[1] Department of Research and Development, Shenzhen Xbiome Biotech Co. Ltd., Shenzhen, China. ^[2] Guangdong Provincial Key Laboratory of Digestive Cancer Research, Digestive Diseases Center, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, China. ^[3]

关键词 Bacteroides anti-PD-1 therapy colorectal cancer fecal microbiota transplantation immunotherapy

主题词动物(Animals);拟杆菌属(Bacteroides);结直肠肿瘤(Colorectal Neoplasms);宏基因组(Metagenome);小鼠(Mice)

DOI 10.3389/fimmu.2022.874922

PMID 35911731

发布时间 2022-08-04

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