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首页> Proceedings of the National Academy of Sciences of the United States of America> P38α MAPK is a gatekeeper of uterine progesterone responsiveness at peri-implantation via Ube3c-mediated PGR degradation.

P38α MAPK is a gatekeeper of uterine progesterone responsiveness at peri-implantation via Ube3c-mediated PGR degradation.

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作者： Yedong,Tang ^[1] ; Jingtao,Qiu ^[2] ; Zhenzhou,Tang ^[2] ; Gaizhen,Li ^[3] ; Mengqing,Gu ^[2] ; Yang,Wang ^[2] ; Haili,Bao ^[2] ; Wenbo,Deng ^[2] ; Zhongxian,Lu ^[2] ; Kinya,Otsu ^[3] ; Zhengchao,Wang ^[4] ; Haibin,Wang ^[1] ; Shuangbo,Kong ^[2]

作者单位： Fujian Provincial Key Laboratory for Developmental Biology and Neurosciences, College of Life Sciences, Fujian Normal University, Fuzhou, Fujian, 350007, China. ^[1] Fujian Provincial Key Laboratory of Reproductive Health Research, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361102, China. ^[2] State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, 361102, China. ^[3] The School of Cardiovascular Medicine and Sciences, King's College London British Heart Foundation Centre of Excellence, London SE5 9NU, United Kingdom. ^[4]

关键词 P38α Ube3c progesterone receptor uterine receptivity

主题词动物(Animals);胚胎植入(Embryo Implantation);子宫内膜(Endometrium);女(雌)性(Female);不育, 女(雌)性(Infertility, Female);MAP激酶信号系统(MAP Kinase Signaling System);丝裂原活化蛋白激酶14(Mitogen-Activated Protein Kinase 14);磷酰化(Phosphorylation);孕酮(Progesterone);受体, 孕酮(Receptors, Progesterone);泛素蛋白连接酶类(Ubiquitin-Protein Ligases);泛素化(Ubiquitination);子宫(Uterus)

DOI 10.1073/pnas.2206000119

PMID 35914132

发布时间 2023-02-02

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Proceedings of the National Academy of Sciences of the United States of America

Proceedings of the National Academy of Sciences of the United States of America

2022年119卷32期

e2206000119页

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Proceedings of the National Academy of Sciences of the United States of America

2022年119卷32期

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