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METTL3 preferentially enhances non-m<sup>6</sup>A translation of epigenetic factors and promotes tumourigenesis.

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作者: Xueju,Wei [1] ; Yue,Huo [2] ; Jingnan,Pi [3] ; Yufeng,Gao [1] ; Shuan,Rao [2] ; Manman,He [1] ; Qinglv,Wei [2] ; Peng,Song [1] ; Yiying,Chen [2] ; Dongxu,Lu [4] ; Wei,Song [1] ; Junbo,Liang [2] ; Lingjie,Xu [1] ; Haixia,Wang [2] ; Guolin,Hong [5] ; Yuehong,Guo [1] ; Yanmin,Si [2] ; Jiayue,Xu [1] ; Xiaoshuang,Wang [2] ; Yanni,Ma [1] ; Shuyang,Yu [2] ; Dongling,Zou [1] ; Jing,Jin [2] ; Fang,Wang [6] ; Jia,Yu [7]
作者单位: State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Haihe Laboratory of Cell Ecosystem, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China. [1] The Key Laboratory of RNA and Hematopoietic Regulation, Chinese Academy of Medical Sciences, Beijing, China. [2] Department of Laboratory Medicine, The First Affiliated Hospital of Xiamen University, Xiamen Key Laboratory of Genetic Testing, School of Medicine, Xiamen University, Xiamen, China. [3] Department of Thoracic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China. [4] Department of Oncology, Second Medical Center of Chinese PLA General Hospital, Beijing, China. [5] Emergency Department of West China Hospital, Sichuan University, Chengdu, China. [6] Department of Gynecologic Oncology, Chongqing University Cancer Hospital &amp; Chongqing Cancer Institute &amp; Chongqing Cancer Hospital, Chongqing, China. [7] State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, China. [8] Department of Gynecologic Oncology, Chongqing University Cancer Hospital &amp; Chongqing Cancer Institute &amp; Chongqing Cancer Hospital, Chongqing, China. cqzl_zdl@163.com. [9] Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. rebeccagold@imm.ac.cn. [10] State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China. rebeccagold@imm.ac.cn. [11] State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Haihe Laboratory of Cell Ecosystem, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China. wo_wfang@hotmail.com. [12] The Key Laboratory of RNA and Hematopoietic Regulation, Chinese Academy of Medical Sciences, Beijing, China. wo_wfang@hotmail.com. [13] State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Haihe Laboratory of Cell Ecosystem, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China. j-yu@ibms.pumc.edu.cn. [14] The Key Laboratory of RNA and Hematopoietic Regulation, Chinese Academy of Medical Sciences, Beijing, China. j-yu@ibms.pumc.edu.cn. [15]
DOI 10.1038/s41556-022-00968-y
PMID 35927451
发布时间 2022-09-29
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