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首页> Cell death & disease> GSDMD-dependent neutrophil extracellular traps promote macrophage-to-myofibroblast transition and renal fibrosis in obstructive nephropathy.

GSDMD-dependent neutrophil extracellular traps promote macrophage-to-myofibroblast transition and renal fibrosis in obstructive nephropathy.

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作者： Yujia,Wang ^[1] ; Yinshuang,Li ^[2] ; Zhimin,Chen ^[1] ; Ying,Yuan ^[2] ; Qinglin,Su ^[1] ; Keng,Ye ^[2] ; Caiming,Chen ^[1] ; Guoping,Li ^[2] ; Yankun,Song ^[1] ; Hong,Chen ^[2] ; Yanfang,Xu ^[1]

作者单位： Department of Nephrology, Blood Purification Research Center, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China. ^[1] Fujian Clinical Research Center for Metabolic Chronic Kidney Disease, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China. ^[2] Department of Pathology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China. ^[3] Department of Pathology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China. fychenhong@126.com. ^[4] Department of Nephrology, Blood Purification Research Center, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China. xuyanfang99@hotmail.com. ^[5] Fujian Clinical Research Center for Metabolic Chronic Kidney Disease, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China. xuyanfang99@hotmail.com. ^[6]

主题词半胱氨酸天冬氨酸蛋白酶(Caspases);纤维化(Fibrosis);人类(Humans);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);肾(Kidney);肾疾病(Kidney Diseases);巨噬细胞(Macrophages);肌成纤维细胞(Myofibroblasts);磷酸结合蛋白质类(Phosphate-Binding Proteins);成孔毒素蛋白质类(Pore Forming Cytotoxic Proteins);信号传导(Signal Transduction);输尿管梗阻(Ureteral Obstruction)

DOI 10.1038/s41419-022-05138-4

PMID 35941120

发布时间 2023-01-19

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Cell death & disease

Cell death & disease

2022年13卷8期

693页

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