首页> Genome biology> Single-cell diploid Hi-C reveals the role of spatial aggregations in complex rearrangements and KMT2A fusions in leukemia.

Single-cell diploid Hi-C reveals the role of spatial aggregations in complex rearrangements and KMT2A fusions in leukemia.

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第一作者： Zhihao,Xing

第一单位： Clinical Laboratory & Division of Hematology and Oncology, Shenzhen Children's Hospital, Shenzhen, China.;Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.;Shenzhen Institute of Pediatrics, Shenzhen Children's Hospital, Shenzhen, China.

作者： Zhihao,Xing ^[1] ; Huirong,Mai ^[2] ; Xiaorong,Liu ^[3] ; Xiaoying,Fu ^[3] ; Xingliang,Zhang ^[4] ; Lichun,Xie ^[2] ; Yunsheng,Chen ^[5] ; Adam,Shlien ^[6] ; Feiqiu,Wen ^[7]

作者单位： Clinical Laboratory & Division of Hematology and Oncology, Shenzhen Children's Hospital, Shenzhen, China.;Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.;Shenzhen Institute of Pediatrics, Shenzhen Children's Hospital, Shenzhen, China. ^[1] Division of Hematology and Oncology, Shenzhen Children's Hospital, Shenzhen, China. ^[2] Clinical Laboratory & Division of Hematology and Oncology, Shenzhen Children's Hospital, Shenzhen, China. ^[3] Shenzhen Institute of Pediatrics, Shenzhen Children's Hospital, Shenzhen, China. ^[4] Clinical Laboratory & Division of Hematology and Oncology, Shenzhen Children's Hospital, Shenzhen, China. chenyunshenglw@163.com. ^[5] Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada. adam.shlien@sickkids.ca. ^[6] Division of Hematology and Oncology, Shenzhen Children's Hospital, Shenzhen, China. fwen62@163.com. ^[7]

关键词 Complex rearrangements Fusions Genomic rearrangements Leukemia Single-cell Hi-C