首页> ACS chemical neuroscience> HDAC3 Inhibitor RGFP966 Ameliorated Neuroinflammation in the Cuprizone-Induced Demyelinating Mouse Model and LPS-Stimulated BV2 Cells by Downregulating the P2X7R/STAT3/NF-κB65/NLRP3 Activation.

HDAC3 Inhibitor RGFP966 Ameliorated Neuroinflammation in the Cuprizone-Induced Demyelinating Mouse Model and LPS-Stimulated BV2 Cells by Downregulating the P2X7R/STAT3/NF-κB65/NLRP3 Activation.

导出 LinkOut

翻译打印收藏纠错

第一作者： Wei,Sun

第一单位： Institute of Biopharmaceutical Research, Liaocheng University, Liaocheng, Shandong 252000, China.

作者： Wei,Sun ^[1] ; Ning,Zhang ^[2] ; Bingyi,Liu ^[1] ; Junrong,Yang ^[1] ; Gabriele,Loers ^[3] ; Hans-Christian,Siebert ^[4] ; Min,Wen ^[1] ; Xuexing,Zheng ^[5] ; Zhengping,Wang ^[1] ; Jun,Han ^[1] ; Ruiyan,Zhang ^[1]

作者单位： Institute of Biopharmaceutical Research, Liaocheng University, Liaocheng, Shandong 252000, China. ^[1] Institute of Biopharmaceutical Research, Liaocheng University, Liaocheng, Shandong 252000, China.;State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China. ^[2] Center for Molecular Neurobiology Hamburg, University Medical Center Hamburg-Eppendorf, University of Hamburg, Falkenried 94, 20251 Hamburg, Germany. ^[3] RI-B-NT - Research Institute of Bioinformatics and Nanotechnology, Schauenburgerstr. 116, 24118 Kiel, Germany. ^[4] Department of Virology, School of Public Health, Shandong University, Jinan 250012, China. ^[5]

关键词 HDAC3 NF-κB NLRP3 P2X7R STAT3 multiple sclerosis