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Obesity impairs skeletal muscle repair through NID-1 mediated extracellular matrix remodeling by mesenchymal progenitors.

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第一作者： Sergio,Pérez-Díaz

第一单位： Univ Paris Est Creteil, INSERM, IMRB, F-94010 Creteil, France.

作者： Sergio,Pérez-Díaz ^[1] ; Zeynab,Koumaiha ^[1] ; Matthew Jay,Borok ^[1] ; Frederic,Aurade ^[2] ; Maria,Pini ^[1] ; Baptiste,Periou ^[1] ; Christine,Rouault ^[3] ; Yasmine,Baba-Amer ^[1] ; Karine,Clément ^[3] ; Genevieve,Derumeaux ^[4] ; François Jérôme,Authier ^[5] ; Peggy,Lafuste ^[1] ; Frederic,Relaix ^[6]

作者单位： Univ Paris Est Creteil, INSERM, IMRB, F-94010 Creteil, France. ^[1] Sorbonne Université, INSERM, UMRS974, Center for Research in Myology, F-75013, Paris, France. ^[2] Sorbonne Université, INSERM, UMRS 1269, Nutrition and obesities ; systemic approaches (NutriOmics), F-75013 Paris, France; Assistance Publique -Hôpitaux de Paris, Nutrition department, Pitié-Salpêtrière hospital, Paris, France. ^[3] Univ Paris Est Creteil, INSERM, IMRB, F-94010 Creteil, France; AP-HP, Hôpital Mondor, FHU SENEC, Service d'Exploration Fonctionnelle, F-94010 Creteil, France. ^[4] Univ Paris Est Creteil, INSERM, IMRB, F-94010 Creteil, France; AP-HP, Hopital Mondor, FHU SENEC, Service d'histologie, F-94010 Creteil, France. ^[5] Univ Paris Est Creteil, INSERM, IMRB, F-94010 Creteil, France; AP-HP, Hopital Mondor, FHU SENEC, Service d'histologie, F-94010 Creteil, France; Ecole nationale vétérinaire d'Alfort, IMRB, F-94700 Maisons-Alfort, France; EFS, IMRB, F-94010 Creteil, France. Electronic address: frederic.relaix@inserm.fr. ^[6]

关键词 FAPs NID-1 Obesity adipose tissue extracellular matrix mesenchymal progenitors muscle regeneration muscle stem cells skeletal muscle