Systematic transcriptome profiling of pyroptosis related signature for predicting prognosis and immune landscape in lower grade glioma.

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第一作者： Huihan,Yu

第一单位： School of Basic Medical Sciences, Anhui Medical University, No. 81, Meishan Road, Hefei, 230032, Anhui, China.

作者： Huihan,Yu ^[1] ; Meiting,Gong ^[2] ; Jian,Qi ^[3] ; Chenggang,Zhao ^[1] ; Wanxiang,Niu ^[2] ; Suling,Sun ^[3] ; Shuyang,Li ^[2] ; Bo,Hong ^[2] ; Junchao,Qian ^[2] ; Hongzhi,Wang ^[2] ; Xueran,Chen ^[1] ; Zhiyou,Fang ^[2]

作者单位： School of Basic Medical Sciences, Anhui Medical University, No. 81, Meishan Road, Hefei, 230032, Anhui, China. ^[1] Anhui Province Key Laboratory of Medical Physics and Technology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, No. 350, Shushan Hu Road, Hefei, 230031, Anhui, China. ^[2] Department of Laboratory Medicine, Hefei Cancer Hospital, Chinese Academy of Sciences, No. 350, Shushan Hu Road, Hefei, 230031, Anhui, China. ^[3] School of Basic Medical Sciences, Anhui Medical University, No. 81, Meishan Road, Hefei, 230032, Anhui, China. wanghz@hfcas.ac.cn. ^[4] Anhui Province Key Laboratory of Medical Physics and Technology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, No. 350, Shushan Hu Road, Hefei, 230031, Anhui, China. wanghz@hfcas.ac.cn. ^[5] Department of Laboratory Medicine, Hefei Cancer Hospital, Chinese Academy of Sciences, No. 350, Shushan Hu Road, Hefei, 230031, Anhui, China. wanghz@hfcas.ac.cn. ^[6] Anhui Province Key Laboratory of Medical Physics and Technology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, No. 350, Shushan Hu Road, Hefei, 230031, Anhui, China. xueranchen@cmpt.ac.cn. ^[7] Department of Laboratory Medicine, Hefei Cancer Hospital, Chinese Academy of Sciences, No. 350, Shushan Hu Road, Hefei, 230031, Anhui, China. xueranchen@cmpt.ac.cn. ^[8] School of Basic Medical Sciences, Anhui Medical University, No. 81, Meishan Road, Hefei, 230032, Anhui, China. zyfang@cmpt.ac.cn. ^[9] Anhui Province Key Laboratory of Medical Physics and Technology; Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, No. 350, Shushan Hu Road, Hefei, 230031, Anhui, China. zyfang@cmpt.ac.cn. ^[10] Department of Laboratory Medicine, Hefei Cancer Hospital, Chinese Academy of Sciences, No. 350, Shushan Hu Road, Hefei, 230031, Anhui, China. zyfang@cmpt.ac.cn. ^[11]

关键词 Drug screening Fedratinib Lower-grade glioma Prognostic signature Pyroptosis Tumor immune microenvironment

主题词脑肿瘤(Brain Neoplasms);基因表达谱(Gene Expression Profiling);神经胶质瘤(Glioma);人类(Humans);预后(Prognosis);肿瘤微环境(Tumor Microenvironment)

DOI 10.1186/s12885-022-09982-7

PMID 35964070

发布时间 2022-08-16

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