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首页> Molecular pain> Persistent inflammatory pain is linked with anxiety-like behaviors, increased blood corticosterone, and reduced global DNA methylation in the rat amygdala.

Persistent inflammatory pain is linked with anxiety-like behaviors, increased blood corticosterone, and reduced global DNA methylation in the rat amygdala.

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作者： Richard L,Spinieli ^[1] ; Rafael Alves,Cazuza ^[1] ; Amanda Juliana,Sales ^[2] ; Ruither Oliveira Gomes,Carolino ^[3] ; Diana,Martinez ^[4] ; Janete,Anselmo-Franci ^[3] ; Maral,Tajerian ^[5] ; Christie Ra,Leite-Panissi ^[6]

作者单位： Department of Psychology, School of Philosophy, Science and Literature of Ribeirão Preto, 28133University of São Paulo, São Paulo, Brazil. ^[1] Department of Pharmacology, Medical School of Ribeirão Preto, 28133University of São Paulo, São Paulo, Brazil. ^[2] Department of Basic and Oral Biology, Dental School of Ribeirão Preto, 28133University of São Paulo, São Paulo, Brazil. ^[3] Department of Biomedical Sciences, 363994Cooper Medical School of Rowan University, Camden, NJ, USA. ^[4] Department of Biology, Queens College, City University of New York, Flushing, NY, USA. ^[5] The Graduate Center, City University of New York, New York, NY, USA. ^[6]

关键词 DNA methylation Persistent inflammatory pain amygdala animal model anxiety disorders corticosterone epigenetics stress

主题词杏仁核(Amygdala);动物(Animals);焦虑(Anxiety);皮质酮(Corticosterone);DNA甲基化(DNA Methylation);后成说, 遗传(Epigenesis, Genetic);Freund佐剂(Freund's Adjuvant);下丘脑-垂体系统(Hypothalamo-Hypophyseal System);男(雄)性(Male);垂体肾上腺系统(Pituitary-Adrenal System);大鼠(Rats);大鼠, Wistar(Rats, Wistar)

DOI 10.1177/17448069221121307

PMID 35974687

发布时间 2022-09-06

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