Kappa opioids inhibit the GABA/glycine terminals of rostral ventromedial medulla projections in the superficial dorsal horn of the spinal cord.

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作者： Yo,Otsu ^[1] ; Karin R,Aubrey ^[2]

作者单位： Pain Management Research, Kolling Institute at the Royal North Shore Hospital NSLHD, University of Sydney, St Leonard, New South Wales, Australia. ^[1] Faculty of Medicine and Health - Northern, Sydney Pain Consortium, University of Sydney, Camperdown, New South Wales, Australia. ^[2]

关键词 IPSC descending pain pathway inhibitory neurotransmission optogenetics raphe-spinal tract substantia gelatinosa

主题词镇痛药, 阿片类(Analgesics, Opioid);甘氨酸(Glycine);受体, 阿片样, κ(Receptors, Opioid, kappa);脊髓(Spinal Cord);γ氨基丁酸(gamma-Aminobutyric Acid)

DOI 10.1113/JP283021

PMID 35979937

发布时间 2022-10-15

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