Schizophrenia-associated differential DNA methylation in brain is distributed across the genome and annotated to MAD1L1, a locus at which DNA methylation and transcription phenotypes share genetic variation with schizophrenia risk.
第一作者:
Brandon C,McKinney
第一单位:
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA. mckinneybc@upmc.edu.;Translational Neuroscience Program, Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA. mckinneybc@upmc.edu.
作者:
医学主题词
脑(Brain);细胞周期蛋白质类(Cell Cycle Proteins);DNA(DNA);DNA甲基化(DNA Methylation);全基因组关联研究(Genome-Wide Association Study);人类(Humans);多态性, 单核苷酸(Polymorphism, Single Nucleotide);精神分裂症(Schizophrenia)
DOI
10.1038/s41398-022-02071-0
PMID
35987687
发布时间
2025-10-31
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