A hyaluronic acid-derived imaging probe for enhanced imaging and accurate staging of liver fibrosis.

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第一作者： Xiaoming,Wang

第一单位： Department of Radiology, Huaxi MR Research Center (HMRRC), Department of Biotherapy, National Clinical Research Center for Geriatrics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China; Department of Radiology, Chongqing General Hospital, No.118, Xingguang Avenue, Liangjiang New Area, Chongqing 401147, China.

作者： Xiaoming,Wang ^[1] ; Xiaoqin,Zhang ^[2] ; Zhiqian,Li ^[3] ; Xueyang,Xiao ^[3] ; Shiwei,Guo ^[4] ; Dayi,Pan ^[3] ; Hu,Zhang ^[5] ; Xiaohe,Tian ^[3] ; Qiyong,Gong ^[6] ; Zhongwei,Gu ^[3] ; Xuelei,Ma ^[7] ; Kui,Luo ^[8]

作者单位： Department of Radiology, Huaxi MR Research Center (HMRRC), Department of Biotherapy, National Clinical Research Center for Geriatrics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China; Department of Radiology, Chongqing General Hospital, No.118, Xingguang Avenue, Liangjiang New Area, Chongqing 401147, China. ^[1] School of Basic Medical Science, Southwest Medical University, Luzhou 646000, China. ^[2] Department of Radiology, Huaxi MR Research Center (HMRRC), Department of Biotherapy, National Clinical Research Center for Geriatrics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China. ^[3] Department of Pharmacy of the Affiliated Hospital of Southwest Medical University, Southwest Medical University, Luzhou, Sichuan Province 646000, China. ^[4] Amgen Bioprocessing Centre, Keck Graduate Institute Claremont, CA 91711, USA. ^[5] Department of Radiology, Huaxi MR Research Center (HMRRC), Department of Biotherapy, National Clinical Research Center for Geriatrics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China; Functional and Molecular Imaging Key Laboratory of Sichuan Province, Research Unit of Psychoradiology, Chinese Academy of Medical Sciences, Chengdu 610041, China. ^[6] Department of Radiology, Huaxi MR Research Center (HMRRC), Department of Biotherapy, National Clinical Research Center for Geriatrics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China. Electronic address: maxuelei0726@wchscu.cn. ^[7] Department of Radiology, Huaxi MR Research Center (HMRRC), Department of Biotherapy, National Clinical Research Center for Geriatrics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China; Functional and Molecular Imaging Key Laboratory of Sichuan Province, Research Unit of Psychoradiology, Chinese Academy of Medical Sciences, Chengdu 610041, China. Electronic address: luokui@scu.edu.cn. ^[8]

关键词 Allysine Hyaluronic acid Liver fibrosis MR imaging

主题词动物(Animals);造影剂(Contrast Media);荧光(Fluorescence);透明质酸(Hyaluronic Acid);肝(Liver);肝硬化(Liver Cirrhosis);磁共振成像(Magnetic Resonance Imaging)

DOI 10.1016/j.carbpol.2022.119870

PMID 35988984

发布时间 2022-08-23

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