Upregulated ClC3 Channels/Transporters Elicit Swelling-Activated Cl<sup>-</sup> Currents and Induce Excessive Cell Proliferation in Idiopathic Pulmonary Arterial Hypertension.

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第一作者： Taiki,Amano

第一单位： Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University.

作者： Taiki,Amano ^[1] ; Aya,Yamamura ^[2] ; Moe,Fujiwara ^[1] ; Seiji,Hirai ^[1] ; Rubii,Kondo ^[1] ; Yoshiaki,Suzuki ^[1] ; Hisao,Yamamura ^[1]

作者单位： Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University. ^[1] Department of Physiology, Aichi Medical University. ^[2]

关键词 ClC3 cell swelling chloride channel proliferation pulmonary artery pulmonary hypertension

主题词人类(Humans);4,4'-二异硫氰基苯-2,2'-二磺酸(4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid);RNA, 小分子干扰(RNA, Small Interfering);肌细胞, 平滑肌(Myocytes, Smooth Muscle);细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured)

DOI 10.1248/bpb.b22-00513

PMID 35989293

发布时间 2022-11-07

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Biological & pharmaceutical bulletin

2022年45卷11期

1684-1691页

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Upregulated ClC3 Channels/Transporters Elicit Swelling-Activated Cl<sup>-</sup> Currents and Induce Excessive Cell Proliferation in Idiopathic Pulmonary Arterial Hypertension.

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Upregulated ClC3 Channels/Transporters Elicit Swelling-Activated Cl<sup>-</sup> Currents and Induce Excessive Cell Proliferation in Idiopathic Pulmonary Arterial Hypertension.

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