Endoplasmic stress-inducing variants in carboxyl ester lipase and pancreatic cancer risk.

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作者： Makoto,Kawamoto ^[1] ; Takeichi,Yoshida ^[1] ; Koji,Tamura ^[1] ; Mohamad,Dbouk ^[1] ; Marcia Irene,Canto ^[2] ; Richard,Burkhart ^[3] ; Jin,He ^[3] ; Nicholas J,Roberts ^[4] ; Alison P,Klein ^[5] ; Michael,Goggins ^[6]

作者单位： Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA. ^[1] Medicine, Johns Hopkins Medical Institutions, Baltimore, MD, USA; Oncology, Johns Hopkins Medical Institutions, Baltimore, MD, USA. ^[2] Surgery, Johns Hopkins Medical Institutions, Baltimore, MD, USA. ^[3] Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA; Oncology, Johns Hopkins Medical Institutions, Baltimore, MD, USA. ^[4] Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA; Oncology, Johns Hopkins Medical Institutions, Baltimore, MD, USA; The Sol Goldman Pancreatic Cancer Research Center, And the Bloomberg School of Public Health, Johns Hopkins Medical Institutions, Baltimore, MD, USA. ^[5] Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA; Medicine, Johns Hopkins Medical Institutions, Baltimore, MD, USA; Oncology, Johns Hopkins Medical Institutions, Baltimore, MD, USA. Electronic address: mgoggins@jhmi.edu. ^[6]

关键词 CEL Endoplasmic reticulum stress Inherited susceptibility Pancreatic cancer Variant

主题词人类(Humans);羧酸酯酶(Carboxylesterase);酯类(Esters);脂肪酶(Lipase);胰腺(Pancreas);胰腺激素类(Pancreatic Hormones);胰腺肿瘤(Pancreatic Neoplasms)

DOI 10.1016/j.pan.2022.08.004

PMID 35995657

发布时间 2023-12-13

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