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Alpha synuclein determines ferroptosis sensitivity in dopaminergic neurons via modulation of ether-phospholipid membrane composition.

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第一作者: Laura,Mahoney-Sanchez
第一单位: Department of Medical Pharmacology, Lille University, INSERM UMRS_1772, Lille University Hospital, LICEND COEN Centre, LilNCog - Lille Neuroscience & Cognition, 59000 Lille, France.
作者单位: Department of Medical Pharmacology, Lille University, INSERM UMRS_1772, Lille University Hospital, LICEND COEN Centre, LilNCog - Lille Neuroscience & Cognition, 59000 Lille, France. [1] Translational Neuroscience, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4365 Esch-sur-Alzette, Luxembourg. [2] Lipid-Aroma Platform, Centre des Sciences Du Goût et de l'Alimentation, UMR6265 CNRS, UMR1324 INRA, Université de Bourgogne, Agrosup Dijon, 21000 Dijon, France. [3] Melbourne Dementia Research Centre, Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, VIC, Australia. [4] Translational Neuroscience, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4365 Esch-sur-Alzette, Luxembourg; Transversal Translational Medicine, Luxembourg Institute of Health (LIH), 1445 Strassen, Luxembourg; Parkinson Reserch Clinic, Centre Hospitalier de Luxembourg (CHL), 1210 Luxembourg (Belair), Luxembourg. [5] Melbourne Dementia Research Centre, Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, VIC, Australia; The ALBORADA Drug Discovery Institute, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK. Electronic address: james.duce@florey.edu.au. [6] Department of Medical Pharmacology, Lille University, INSERM UMRS_1772, Lille University Hospital, LICEND COEN Centre, LilNCog - Lille Neuroscience & Cognition, 59000 Lille, France. Electronic address: david.devos@chru-lille.fr. [7] Department of Medical Pharmacology, Lille University, INSERM UMRS_1772, Lille University Hospital, LICEND COEN Centre, LilNCog - Lille Neuroscience & Cognition, 59000 Lille, France; Université Du Litoral Côte D'Opale, 1, Place de l'Yser, Dunkerque Cedex, France. [8]
DOI 10.1016/j.celrep.2022.111231
PMID 36001957
发布时间 2025-05-30
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