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Krüppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency.

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第一作者: Zhipeng,Ai
第一单位: Division of Human Reproduction and Developmental Genetics, Women's Hospital, and Institute of Genetics, Zhejiang University School of Medicine, Hangzhou 310006, China.
作者: Zhipeng,Ai [1] ; Xinyu,Xiang [2] ; Yangquan,Xiang [1] ; Iwona,Szczerbinska [3] ; Yuli,Qian [4] ; Xiao,Xu [1] ; Chenyang,Ma [1] ; Yaqi,Su [2] ; Bing,Gao [2] ; Hao,Shen [1] ; Muhammad Nadzim,Bin Ramli [3] ; Di,Chen [2] ; Yue,Liu [5] ; Jia-Jie,Hao [5] ; Huck Hui,Ng [6] ; Dan,Zhang [7] ; Yun-Shen,Chan [8] ; Wanlu,Liu [9] ; Hongqing,Liang [10]
作者单位: Division of Human Reproduction and Developmental Genetics, Women's Hospital, and Institute of Genetics, Zhejiang University School of Medicine, Hangzhou 310006, China. [1] Zhejiang University-University of Edinburgh Institute (ZJU-UoE Institute), Zhejiang University School of Medicine, International Campus, Zhejiang University, 718 East Haizhou Road, Haining 314400, China. [2] Stem Cell and Regenerative Biology, Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672, Singapore. [3] Key Laboratory of Reproductive Genetics (Ministry of Education) and Department of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China. [4] Guangzhou Laboratory, No. 9 Xing Dao Huan Bei Road, Guangzhou International Bio Island, Guangzhou 510005, China. [5] Stem Cell and Regenerative Biology, Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672, Singapore; Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore 117597, Singapore; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 639798, Singapore. [6] Key Laboratory of Reproductive Genetics (Ministry of Education) and Department of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China. Electronic address: zhangdan@zju.edu.cn. [7] Stem Cell and Regenerative Biology, Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672, Singapore; Guangzhou Laboratory, No. 9 Xing Dao Huan Bei Road, Guangzhou International Bio Island, Guangzhou 510005, China. Electronic address: chan_yunshen@gzlab.ac.cn. [8] Zhejiang University-University of Edinburgh Institute (ZJU-UoE Institute), Zhejiang University School of Medicine, International Campus, Zhejiang University, 718 East Haizhou Road, Haining 314400, China; Department of Orthopedic Surgery of the Second Affiliated Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou 310029, China; Dr. Li Dak Sum & Yip Yio Chin Center for Stem Cell and Regenerative Medicine, Zhejiang University, Hangzhou 310058, China. Electronic address: wanluliu@intl.zju.edu.cn. [9] Division of Human Reproduction and Developmental Genetics, Women's Hospital, and Institute of Genetics, Zhejiang University School of Medicine, Hangzhou 310006, China. Electronic address: lianghongqing@zju.edu.cn. [10]
DOI 10.1016/j.celrep.2022.111240
PMID 36001968
发布时间 2025-10-31
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