An Anticancer Rhenium Tricarbonyl Targets Fe-S Cluster Biogenesis in Ovarian Cancer Cells.

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第一作者： Benjamin,Neuditschko

第一单位： Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, 1090, Vienna, Austria.

作者： Benjamin,Neuditschko ^[1] ; A Paden,King ^[2] ; Zhouyang,Huang ^[3] ; Lukas,Janker ^[4] ; Andrea,Bileck ^[5] ; Yasmin,Borutzki ^[4] ; Sierra C,Marker ^[1] ; Christopher,Gerner ^[6] ; Justin J,Wilson ^[1] ; Samuel M,Meier-Menches ^[6]

作者单位： Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, 1090, Vienna, Austria. ^[1] Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, 1090, Vienna, Austria. ^[2] Present address: Institute Krems Bioanalytics, IMC University of Applied Sciences Krems, 3500, Krems, Austria. ^[3] Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA. ^[4] Present address: Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA. ^[5] Joint Metabolome Facility, University of Vienna and Medical University Vienna, 1090, Vienna, Austria. ^[6]

关键词 Cancer Mode of Action Proteomics Rhenium Target Identification

主题词人类(Humans);女(雌)性(Female);铼(Rhenium);铁硫蛋白质类(Iron-Sulfur Proteins);线粒体(Mitochondria);卵巢肿瘤(Ovarian Neoplasms);铁蛋白质类(Ferritins)

DOI 10.1002/anie.202209136

PMID 36004624

发布时间 2023-01-11

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