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首页> Experimental parasitology> Host P2X<sub>7</sub>R-p<sub>38</sub>MAPK axis mediated intra-macrophage leishmanicidal activity of Spergulin-A.

Host P2X<sub>7</sub>R-p<sub>38</sub>MAPK axis mediated intra-macrophage leishmanicidal activity of Spergulin-A.

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作者： Niladri,Mukherjee ^[1] ; Saswati,Banerjee ^[2] ; Sk Abdul,Amin ^[3] ; Tarun,Jha ^[3] ; Sriparna,Datta ^[4] ; Krishna,Das Saha ^[5]

作者单位： Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Kolkata, 700032, India; Techno India University, EM-4, Sector V, Salt Lake, Kolkata, 700091, West Bengal, India. Electronic address: niladrizoology@gmail.com. ^[1] Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Kolkata, 700032, India. ^[2] Natural Science Laboratory, Department of Pharmaceutical Technology, Division of Medicinal & Pharmaceutical Chemistry, P. O. Box 17020, Jadavpur University, Kolkata, 700032, India. ^[3] Department of Chemical Technology, University of Calcutta, Kolkata, 700009, India. ^[4] Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Kolkata, 700032, India. Electronic address: krishna@iicb.res.in. ^[5]

关键词 In vivo validation Leishmania donovani NF-κβp65 P2X(7) receptor Spergulin-A p38MAPK

主题词动物(Animals);载体蛋白质类(Carrier Proteins);杜氏利什曼原虫(Leishmania donovani);利什曼病, 内脏(Leishmaniasis, Visceral);巨噬细胞(Macrophages);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);受体, 嘌呤能P2X7(Receptors, Purinergic P2X7);信号传导(Signal Transduction);脾(Spleen);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases)

DOI 10.1016/j.exppara.2022.108365

PMID 36007587

发布时间 2022-09-22

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Experimental parasitology

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