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Prevention of Anti-HMGCR Immune-Mediated Necrotising Myopathy by C5 Complement Inhibition in a Humanised Mouse Model.

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第一作者： Sarah,Julien

第一单位： INSERM U1234, PAn'THER FOCIS Center of Excellence, Université de Rouen, F-76000 Rouen, France.

作者： Sarah,Julien ^[1] ; Douangsone,Vadysirisack ^[2] ; Camil,Sayegh ^[2] ; Sharan,Ragunathan ^[2] ; Yalan,Tang ^[2] ; Emma,Briand ^[1] ; Marion,Carrette ^[1] ; Laetitia,Jean ^[1] ; Rachid,Zoubairi ^[1] ; Henri,Gondé ^[1] ; Olivier,Benveniste ^[3] ; Yves,Allenbach ^[3] ; Laurent,Drouot ^[1] ; Olivier,Boyer ^[1]

作者单位： INSERM U1234, PAn'THER FOCIS Center of Excellence, Université de Rouen, F-76000 Rouen, France. ^[1] UCB Pharma, Cambridge, 02140 MA, USA. ^[2] Department of Internal Medicine and Clinical Immunology, Pitié-Salpêtrière University Hospital, Sorbonne Université, Inserm, U974, F-75013 Paris, France. ^[3]

关键词 HMGCR autoantibody complement immune-mediated necrotising myopathy myositis

DOI 10.3390/biomedicines10082036

PMID 36009583

发布时间 2022-08-30

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Prevention of Anti-HMGCR Immune-Mediated Necrotising Myopathy by C5 Complement Inhibition in a Humanised Mouse Model.

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Prevention of Anti-HMGCR Immune-Mediated Necrotising Myopathy by C5 Complement Inhibition in a Humanised Mouse Model.

Biomedicines

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