Improvements in Quality Control and Library Preparation for Targeted Sequencing Allowed Detection of Potentially Pathogenic Alterations in Circulating Cell-Free DNA Derived from Plasma of Brain Tumor Patients.

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第一作者： Paulina,Szadkowska

第一单位： Nencki Institute of Experimental Biology, 02-093 Warsaw, Poland.

作者： Paulina,Szadkowska ^[1] ; Adria-Jaume,Roura ^[2] ; Bartosz,Wojtas ^[1] ; Kamil,Wojnicki ^[1] ; Sabina,Licholai ^[1] ; Tomasz,Waller ^[3] ; Tomasz,Gubala ^[3] ; Kacper,Zukowski ^[3] ; Michal,Karpeta ^[4] ; Kinga,Wilkus ^[3] ; Wojciech,Kaspera ^[5] ; Sergiusz,Nawrocki ^[2] ; Bozena,Kaminska ^[5]

作者单位： Nencki Institute of Experimental Biology, 02-093 Warsaw, Poland. ^[1] Postgraduate School of Molecular Medicine, Medical University of Warsaw, 02-007 Warsaw, Poland. ^[2] Academic Computer Centre CYFRONET AGH, 30-950 Krakow, Poland. ^[3] Sano Centre for Computational Medicine, 30-054 Krakow, Poland. ^[4] Regional Science and Technology Centre, 26-060 Podzamcze, Poland. ^[5] Department of Neurosurgery, Medical University of Silesia, Regional Hospital, 41-200 Sosnowiec, Poland. ^[6] Department of Oncology, University of Warmia and Mazury in Olsztyn, 10-228 Olsztyn, Poland. ^[7]

关键词 ccfDNA circulating tumor DNA glioma liquid biopsy targeted NGS

DOI 10.3390/cancers14163902

PMID 36010895

发布时间 2022-08-30

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