Design, synthesis, and evaluation of novel 3,4-isoxazolediamide derivatives for the combination treatment of azole-resistant candidiasis.
第一作者:
Lei,Liu
第一单位:
Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, China.
作者:
医学主题词
人类(Humans);抗真菌药(Antifungal Agents);氮杂茂类(Azoles);白色念珠菌(Candida albicans);念珠菌病(Candidiasis);抗药性, 真菌(Drug Resistance, Fungal);HSP90热休克蛋白质类(HSP90 Heat-Shock Proteins);微生物敏感性试验(Microbial Sensitivity Tests);构效关系(Structure-Activity Relationship)
DOI
10.1002/ardp.202200266
PMID
36029272
发布时间
2022-12-05
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Archiv der Pharmazie
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