AAV-mediated rescue of <i>Eps8</i> expression <i>in vivo</i> restores hair-cell function in a mouse model of recessive deafness.

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作者： Jing-Yi,Jeng ^[1] ; Adam J,Carlton ^[1] ; Richard J,Goodyear ^[2] ; Colbie,Chinowsky ^[3] ; Federico,Ceriani ^[1] ; Stuart L,Johnson ^[1] ; Tsung-Chang,Sung ^[4] ; Yelena,Dayn ^[5] ; Guy P,Richardson ^[5] ; Michael R,Bowl ^[2] ; Steve D M,Brown ^[6] ; Uri,Manor ^[6] ; Walter,Marcotti ^[3]

作者单位： School of Bioscience, University of Sheffield, Sheffield S10 2TN, UK. ^[1] Sussex Neuroscience, School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, UK. ^[2] Waitt Advanced Biophotonics Center, Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA. ^[3] Neuroscience Institute, University of Sheffield, Sheffield S10 2TN, UK. ^[4] Transgenic Core, Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA. ^[5] Mammalian Genetics Unit, MRC Harwell Institute, Harwell Campus, Oxfordshire OX11 0RD UK. ^[6]

关键词 AAVs Eps8 auditory cochlea deafness development exocytosis gene therapy mouse stereocilia

DOI 10.1016/j.omtm.2022.07.012

PMID 36034774

发布时间 2024-05-16

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Molecular therapy. Methods & clinical development

2022年26卷

355-370页

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AAV-mediated rescue of <i>Eps8</i> expression <i>in vivo</i> restores hair-cell function in a mouse model of recessive deafness.

Molecular therapy. Methods & clinical development

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Molecular therapy. Methods & clinical development

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AAV-mediated rescue of <i>Eps8</i> expression <i>in vivo</i> restores hair-cell function in a mouse model of recessive deafness.

Molecular therapy. Methods & clinical development

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Molecular therapy. Methods & clinical development

相关期刊

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