Brigatinib in Japanese patients with tyrosine kinase inhibitor-naive ALK-positive non-small cell lung cancer: first results from the phase 2 J-ALTA study.

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第一作者： Shunichi,Sugawara

第一单位： Department of Pulmonary Medicine, Sendai Kousei Hospital, Miyagi, Japan.

作者： Shunichi,Sugawara ^[1] ; Masashi,Kondo ^[2] ; Toshihide,Yokoyama ^[3] ; Toru,Kumagai ^[4] ; Makoto,Nishio ^[5] ; Koichi,Goto ^[6] ; Kazuhiko,Nakagawa ^[7] ; Takashi,Seto ^[8] ; Nobuyuki,Yamamoto ^[9] ; Kentarou,Kudou ^[10] ; Takayuki,Asato ^[11] ; Pingkuan,Zhang ^[12] ; Yuichiro,Ohe ^[13]

作者单位： Department of Pulmonary Medicine, Sendai Kousei Hospital, Miyagi, Japan. ^[1] Department of Respiratory Medicine, Fujita Health University School of Medicine, Toyoake, Japan. ^[2] Department of Respiratory Medicine, Kurashiki Central Hospital, Kurashiki, Japan. ^[3] Department of Thoracic Oncology, Osaka International Cancer Institute, Osaka, Japan. ^[4] Department of Thoracic Medical Oncology, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan. ^[5] Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan. ^[6] Department of Medical Oncology, Faculty of Medicine, Kindai University, Osaka-Sayama, Japan. ^[7] Department of Thoracic Oncology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan. ^[8] Internal Medicine III, Wakayama Medical University, Wakayama, Japan. ^[9] Biostatistics, Japan Development Center, Takeda Pharmaceutical Company Limited, Osaka, Japan. ^[10] Oncology Clinical Research Department, Oncology Therapeutic Area Unit for Japan and Asia, Takeda Pharmaceutical Company Limited, Osaka, Japan. ^[11] Takeda Development Center Americas, Inc., Lexington, MA, USA. ^[12] Department of Thoracic Oncology, National Cancer Center Hospital, 5-1-1 Tsukiji Chuo-ku, Tokyo, 104-0045, Japan. yohe@ncc.go.jp. ^[13]

关键词 Anaplastic lymphoma kinase Carcinoma Non-small cell lung Tyrosine kinase inhibitor

主题词人类(Humans);中年人(Middle Aged);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);蛋白酪氨酸激酶类(Protein-Tyrosine Kinases);肺肿瘤(Lung Neoplasms);日本(Japan);蛋白激酶抑制剂(Protein Kinase Inhibitors)

DOI 10.1007/s10147-022-02232-7

PMID 36036294

发布时间 2023-03-22

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