Decoding the effects of spike receptor binding domain mutations on antibody escape abilities of omicron variants.

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第一作者： Sandipan,Chakraborty

第一单位： Center for Innovation in Molecular and Pharmaceutical Sciences (CIMPS), Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500046, India. Electronic address: sandipanchakraborty.13@gmail.com.

作者： Sandipan,Chakraborty ^[1] ; Aditi,Saha ^[2] ; Chiranjeet,Saha ^[2] ; Sanjana,Ghosh ^[2] ; Trisha,Mondal ^[2]

作者单位： Center for Innovation in Molecular and Pharmaceutical Sciences (CIMPS), Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500046, India. Electronic address: sandipanchakraborty.13@gmail.com. ^[1] Amity Institute of Biotechnology, Amity University, Kolkata, 700135, India. ^[2]

关键词 Antibody escape Binding affinity Immunogenic hotspot Mutations Omicron variants

主题词抗体, 单克隆(Antibodies, Monoclonal);抗体, 中和(Antibodies, Neutralizing);结合部位(Binding Sites);人类(Humans);突变(Mutation)

DOI 10.1016/j.bbrc.2022.08.050

PMID 36041326

发布时间 2022-10-12

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