Immune checkpoint receptor VISTA on immune cells is associated with expression of T-cell exhaustion marker TOX and worse prognosis in renal cell carcinoma with venous tumor thrombus.

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第一作者： Łukasz,Zapała

第一单位： Clinic of General, Oncological and Functional Urology, Medical University of Warsaw, Lindleya 4, 02-005, Warsaw, Poland. lzapala@wum.edu.pl.

作者： Łukasz,Zapała ^[1] ; Michał,Kunc ^[2] ; Sumit,Sharma ^[3] ; Rafał,Pęksa ^[2] ; Marta,Popęda ^[2] ; Wojciech,Biernat ^[4] ; Piotr,Radziszewski ^[2]

作者单位： Clinic of General, Oncological and Functional Urology, Medical University of Warsaw, Lindleya 4, 02-005, Warsaw, Poland. lzapala@wum.edu.pl. ^[1] Department of Pathomorphology, Medical University of Gdansk, 80-214, Gdańsk, Poland. ^[2] Clinic of General, Oncological and Functional Urology, Medical University of Warsaw, Lindleya 4, 02-005, Warsaw, Poland. ^[3] Laboratory of Translational Oncology, Intercollegiate Faculty of Biotechnology, Medical University of Gdańsk, 80-211, Gdańsk, Poland. ^[4]

关键词 PD-L1 Renal cell carcinoma TOX Thrombus Tumor microenvironment VISTA

主题词女(雌)性(Female);人类(Humans);癌, 肾细胞(Carcinoma, Renal Cell);肾肿瘤(Kidney Neoplasms);预后(Prognosis);血栓形成(Thrombosis)

DOI 10.1007/s00432-022-04329-y

PMID 36042047

发布时间 2023-07-07

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