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Detection of ALK fusion variants by RNA-based NGS and clinical outcome correlation in NSCLC patients treated with ALK-TKI sequences.

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作者单位: Department of Oncology, University of Turin, San Luigi Gonzaga Hospital, 10043, Orbassano, TO, Italy. Electronic address: fabrizio.tabbo@unito.it. [1] Laboratory of Oncology, Fondazione IRCCS Casa Sollievo Della Sofferenza Hospital, San Giovanni Rotondo, Foggia, Italy. [2] Cancer Research Center Lyon, Centre Léon Bérard, 28 Rue Laennec, 69373, Lyon, France; Thoracic Oncology Unit, CHU Grenoble, Avenue Maquis Du Grésivaudan, 38700, La Tronche, France. [3] Bioinformatic Unit, Fondazione IRCCS Casa Sollievo Della Sofferenza Hospital, San Giovanni Rotondo, Foggia, Italy. [4] Department of Oncology, University of Turin, San Luigi Gonzaga Hospital, 10043, Orbassano, TO, Italy. [5] Medical Thoracic Unit, IRCCS Istituto Tumori Giovanni Paolo II, Viale Orazio Flacco 65, 70124, Bari, Italy. [6] Oncology Unit, Fondazione IRCCS Casa Sollievo Della Sofferenza Hospital, Viale Cappuccini 1, 71013, San Giovanni Rotondo, Italy. [7] Medical Oncology Unit, San Giovanni Addolorata Hospital, Via Dell'Amba Aradam 9, 00184, Rome, Italy. [8] Medical Oncology Unit, University Hospital, Via Gramsci 14, 43123, Parma, Italy; Department of Medicine and Surgery, University of Parma, Via Gramsci 14, 43123, Parma, Italy. [9] Radiotherapy Unit, University Hospital Careggi, Largo Brambilla 3, 50134, Firenze, Italy. [10] Oncology Department, Papa Giovanni XXIII Hospital, Piazza OMS 1, 24127, Bergamo, Italy. [11] Department of Medical Oncology, Istituto di Ricovero e Cura a Carattere Scientifico, San Raffaele Hospital, Via Olgettina Milano 60, 20132, Milano, Italy. [12] Oncology Unit, A.O.R.N.A.S Garibaldi Nesima, Via Palermo 636, 95100, Catania, Italy. [13] Oncology Unit, Department of Medicine, University of Verona, Piazzale L.A. Scuro 10, 37134, Verona, Italy. [14] Medical Oncology and Immuno-Related Tumors Unit, Centro di Riferimento Oncologico (CRO) IRCCS, Via Gallini 2, 33081, Aviano, Italy. [15] Istituto Nazionale Tumori IRCCS Regina Elena, Via E. Chianesi 53, 00144, Roma, Italy. [16] Oncology Unit, ASST San Gerardo Hospital, Via G. B. Pergolesi 33, 20900 Monza, Italy. [17] UOSD Pneumologia Oncologica, San Camillo Forlanini Hospital, Circonvallazione Gianicolense 87, 00152, Roma, Italy. [18] Oncology Unit, IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122, Milan, Italy. [19] Department of Oncology, University of Turin, Mauriziano Hospital, Largo F. Turati 62, 10128, Torino, Italy. [20] Operative Unit of Pathologic Anatomy, Azienda Unità Sanitaria Locale Della Romagna, Hospital St. Maria Delle Croci, Viale V. Randi 5, 48121, Ravenna, Italy. [21] Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo A. Gemelli 8, 00168, Roma, Italy; Section of Oncology, Department of Translational Medicine, Università Cattolica Del Sacro Cuore, Largo F. Vito 1, 00168, Roma, Italy. [22] Pathology Unit, Fondazione IRCCS Casa Sollievo Della Sofferenza Hospital, Viale Cappuccini 1, 71013, San Giovanni Rotondo, FG, Italy. [23]
DOI 10.1016/j.ejca.2022.07.026
PMID 36044814
发布时间 2022-11-08
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