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Gut microbial DL-endopeptidase alleviates Crohn's disease via the NOD2 pathway.

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第一作者: Jie,Gao
第一单位: Microbiome Medicine Center, Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510655, China.
作者: Jie,Gao [1] ; Xinmei,Zhao [2] ; Shixian,Hu [3] ; Zhenhe,Huang [1] ; Mengyao,Hu [1] ; Shaoqin,Jin [4] ; Bingyun,Lu [5] ; Kai,Sun [6] ; Zhang,Wang [7] ; Jingyuan,Fu [8] ; Rinse K,Weersma [9] ; Xiaolong,He [10] ; Hongwei,Zhou [11]
作者单位: Microbiome Medicine Center, Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510655, China. [1] Guangdong Provincial Key Laboratory of Gastroenterology, Institute of Gastroenterology of Guangdong Province, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China. [2] Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen 9713 AV, the Netherlands; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen 9713 AV, the Netherlands. [3] Department of Gastroenterology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. [4] Department of Gastroenterology, Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong 518101, China. [5] Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China. [6] Institute of Ecological Sciences, School of Life Sciences, South China Normal University, Guangzhou, Guangdong 510515, China. [7] Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen 9713 AV, the Netherlands; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands. [8] Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen 9713 AV, the Netherlands. Electronic address: r.k.weersma@mdl.umcg.nl. [9] Microbiome Medicine Center, Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510655, China; Department of Microbiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, Guangdong 510515, China. Electronic address: hxl2027315@smu.edu.cn. [10] Microbiome Medicine Center, Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510655, China; State Key Laboratory of Organ Failure Research, Southern Medical University, Guangzhou, Guangdong 510515, China. Electronic address: biodegradation@gmail.com. [11]
DOI 10.1016/j.chom.2022.08.002
PMID 36049483
发布时间 2022-12-16
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