首页> Frontiers in immunology> Myeloid checkpoint blockade improves killing of T-acute lymphoblastic leukemia cells by an IgA2 variant of daratumumab.

Myeloid checkpoint blockade improves killing of T-acute lymphoblastic leukemia cells by an IgA2 variant of daratumumab.

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第一作者： Niklas,Baumann

第一单位： Division of Stem Cell Transplantation and Immunotherapy, Department of Medicine II, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.

作者： Niklas,Baumann ^[1] ; Christian,Arndt ^[1] ; Judith,Petersen ^[1] ; Marta,Lustig ^[1] ; Thies,Rösner ^[1] ; Katja,Klausz ^[2] ; Christian,Kellner ^[3] ; Miriam,Bultmann ^[4] ; Lorenz,Bastian ^[4] ; Fotini,Vogiatzi ^[5] ; Jeanette H W,Leusen ^[6] ; Renate,Burger ^[1] ; Denis M,Schewe ^[7] ; Matthias,Peipp ^[2] ; Thomas,Valerius ^[1]

作者单位： Division of Stem Cell Transplantation and Immunotherapy, Department of Medicine II, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany. ^[1] Division of Antibody-Based Immunotherapy, Department of Medicine II, Christian- Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany. ^[2] Division of Transfusion Medicine, Cell Therapeutics and Haemostaseology, University Hospital, LMU Munich, Munich, Germany. ^[3] Department of Medicine II, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany. ^[4] Pediatric Hematology/Oncology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany. ^[5] Center for Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands. ^[6] Children's Hospital, University Medical Center Magdeburg, Magdeburg, Germany. ^[7]

关键词 CD38 CD47 IgA SIRPα T-cell acute lymphoblastic leukemia (T-ALL)daratumumab immunotherapy

医学主题词抗体, 单克隆(Antibodies, Monoclonal);人类(Humans);免疫球蛋白A(Immunoglobulin A);前体T细胞淋巴母细胞白血病淋巴瘤(Precursor T-Cell Lymphoblastic Leukemia-Lymphoma)

DOI 10.3389/fimmu.2022.949140

PMID 36052078

发布时间 2022-09-14

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