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Evaluation of commonly used cardiovascular drugs in inhibiting vonoprazan metabolism in vitro and in vivo.

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第一作者： Yiran,Wang

第一单位： Department of Gastroenterology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.;Peking University Fifth School of Clinical Medicine, Beijing, China.

作者： Yiran,Wang ^[1] ; Jihua,Shi ^[2] ; Dapeng,Dai ^[3] ; Jianping,Cai ^[3] ; Shuanghu,Wang ^[4] ; Yun,Hong ^[2] ; Shan,Zhou ^[3] ; Fangling,Zhao ^[5] ; Quan,Zhou ^[4] ; Peiwu,Geng ^[4] ; Yunfang,Zhou ^[4] ; Xue,Xu ^[2] ; Qingfeng,Luo ^[2]

作者单位： Department of Gastroenterology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.;Peking University Fifth School of Clinical Medicine, Beijing, China. ^[1] Department of Gastroenterology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China. ^[2] The Key Laboratory of Geriatrics, Beijing Institute of Geriatrics, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital/National Center of Gerontology of National Health Commission, Beijing, China. ^[3] Laboratory of Clinical Pharmacy, The Sixth Affiliated Hospital of Wenzhou Medical University, The People's Hospital of Lishui, Lishui, China. ^[4] The Key Laboratory of Geriatrics, Beijing Institute of Geriatrics, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital/National Center of Gerontology of National Health Commission, Beijing, China.;Peking University Fifth School of Clinical Medicine, Beijing, China. ^[5]

关键词 cardiovascular drugs cytochrome P450 drug metabolism drug–drug interactions vonoprazan metabolism

DOI 10.3389/fphar.2022.909168

PMID 36052128

发布时间 2022-09-07

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