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首页> Fitoterapia> Schisantherin D from Schisandra chinensis (Turcz.) Baill. exhibits anti-liver fibrosis capacity via modulating ETBR involved signaling, an in vitro and in vivo study.

Schisantherin D from Schisandra chinensis (Turcz.) Baill. exhibits anti-liver fibrosis capacity via modulating ETBR involved signaling, an in vitro and in vivo study.

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第一作者： Chi,Li

第一单位： Department of Pharmacy, College of Medicine, Jiaxing University, Jiaxing 314001, China.

作者： Chi,Li ^[1] ; Yang-Jie,Ru ^[1] ; Quan-Yue,Lin ^[1] ; Guang-Chun,Gao ^[1] ; Yu-Die,Yang ^[1] ; Xiao-Qin,Zhang ^[1] ; Jin-Lai,Gao ^[1] ; Shi-Hui,Liu ^[1] ; Chu-Wei,Zheng ^[2] ; Lin,Wang ^[3] ; Ya-Xin,Zheng ^[4] ; Ji-Ming,Wu ^[5]

作者单位： Department of Pharmacy, College of Medicine, Jiaxing University, Jiaxing 314001, China. ^[1] Department of Gastroenterology, The Second Hospital of Jiaxing, Jiaxing 314001, China. ^[2] Department of Pharmacy, College of Medicine, China Three Gorges University, Yichang 610500, China. ^[3] School of Pharmacy, Key Laboratory of Sichuan Province for Specific Structure of Small Molecule Drugs, Chengdu Medical College, Chengdu 610500, China. ^[4] Department of Pharmacy, College of Medicine, Jiaxing University, Jiaxing 314001, China. Electronic address: wjmwtw@126.com. ^[5]

关键词 ETBR Functional mechanisms Liver fibrosis Schisantherin D Signaling pathways

主题词醋氨酚(Acetaminophen);黄曲霉毒素B1(Aflatoxin B1);动物(Animals);二恶茂类(Dioxoles);人类(Humans);木酚素类(Lignans);肝硬化(Liver Cirrhosis);小鼠(Mice);分子结构(Molecular Structure);NF-E2相关因子2(NF-E2-Related Factor 2);受体, 内皮素B(Receptor, Endothelin B);五味子属(Schisandra);转化生长因子β(Transforming Growth Factor beta);转化生长因子β1(Transforming Growth Factor beta1);肿瘤坏死因子α(Tumor Necrosis Factor-alpha)

DOI 10.1016/j.fitote.2022.105290

PMID 36064152

发布时间 2022-10-06

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