Comparison of assay formats used for the detection of pre-existing anti-drug antibodies against monoclonal antibodies.

导出 LinkOut

翻译打印收藏纠错

作者： Alexander,Pöhler ^[1] ; Thomas,Emrich ^[1] ; Gregor,Jordan ^[1] ; Martin,Schäfer ^[1] ; Kay-Gunnar,Stubenrauch ^[1] ; Roland F,Staack ^[1] ; Carolin,Zach ^[1] ; Julian,Meir ^[1] ; Janine,Faigle ^[1]

作者单位： Roche Pharma Research & Early Development (pRED), Pharmaceutical Sciences, Bioanalysis & Biomarkers, Roche Innovation Center Munich, Roche Diagnostics GmbH, Nonnenwald 2, 82377 Penzberg, Germany. ^[1]

关键词 ADA bridging assay human autoantibodies immune-complex ADA assay immunogenicity pre-existing anti-drug antibodies preADA

主题词抗体, 单克隆(Antibodies, Monoclonal);抗原抗体复合物(Antigen-Antibody Complex)

DOI 10.4155/bio-2022-0085

PMID 36066084

发布时间 2022-09-14

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交