Pharmacological ascorbate as a novel therapeutic strategy to enhance cancer immunotherapy.

导出 LinkOut

翻译打印收藏纠错

作者： Amira,Zaher ^[1] ; Laura M,Stephens ^[2] ; Ann M,Miller ^[2] ; Stacey M,Hartwig ^[2] ; Jeffrey M,Stolwijk ^[3] ; Michael S,Petronek ^[3] ; Zeb R,Zacharias ^[4] ; Thaddeus J,Wadas ^[5] ; Varun,Monga ^[6] ; Joseph J,Cullen ^[7] ; Muhammad,Furqan ^[6] ; Jon C D,Houtman ^[2] ; Steven M,Varga ^[2] ; Douglas R,Spitz ^[3] ; Bryan G,Allen ^[3]

作者单位： Cancer Biology Program, Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, IA, United States. ^[1] Department of Microbiology and Immunology, The University of Iowa, Iowa City, IA, United States. ^[2] Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, IA, United States. ^[3] Human Immunology Core & Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, IA, United States. ^[4] Department of Radiology, Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, IA, United States. ^[5] Division of Hematology, Oncology, and Blood & Marrow Transplantation, Department of Internal Medicine, Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, IA, United States. ^[6] Department of Surgery, Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, IA, United States. ^[7]

关键词 anti-PD-1 antioxidant therapy cancer immunotherapy immune checkpoint inhibitors immune regulation pharmacological ascorbate prooxidant therapy

主题词抗肿瘤药(Antineoplastic Agents);抗坏血酸(Ascorbic Acid);人类(Humans);免疫疗法(Immunotherapy);肿瘤(Neoplasms)

DOI 10.3389/fimmu.2022.989000

PMID 36072595

发布时间 2023-07-01

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交