Accurate tumor clonal structures require single-cell analysis.

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作者： Xianbin,Su ^[1] ; Shihao,Bai ^[1] ; Gangcai,Xie ^[2] ; Yi,Shi ^[3] ; Linan,Zhao ^[1] ; Guoliang,Yang ^[4] ; Futong,Tian ^[5] ; Kun-Yan,He ^[1] ; Lan,Wang ^[1] ; Xiaolin,Li ^[1] ; Qi,Long ^[6] ; Ze-Guang,Han ^[1]

作者单位： Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China. ^[1] Institute of Reproductive Medicine, Medical School of Nantong University, Nantong, China. ^[2] Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Shanghai Jiao Tong University, Shanghai, China. ^[3] Department of Urology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. ^[4] Department of Design, Politecnico di Milano, Milan, Italy. ^[5] Joint School of Life Sciences, Guangzhou Medical University & Guangzhou Institutes of Biomedicine and Health-Chinese Academy of Sciences, Guangzhou, China. ^[6]

关键词 clonal structure genetic heterogeneity single-cell analysis tumor evolution variant allele frequency

主题词人类(Humans);单细胞分析(Single-Cell Analysis);肿瘤(Neoplasms);突变(Mutation)

DOI 10.1111/nyas.14897

PMID 36081327

发布时间 2022-12-14

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