Sclerostin aggravates insulin signaling in skeletal muscle and hepatic steatosis via upregulation of ER stress by mTOR-mediated inhibition of autophagy under hyperlipidemic conditions.
第一作者:
Heeseung,Oh
第一单位:
Department of Pharmacology, College of Medicine, Chung-Ang University, Seoul, Republic of Korea.
作者:
主题词
人类(Humans);小鼠(Mice);动物(Animals);增量调节(Up-Regulation);胰岛素(Insulin);胰岛素抗药性(Insulin Resistance);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases);脂肪肝(Fatty Liver);自噬(Autophagy);肌, 骨骼(Muscle, Skeletal);肥胖症(Obesity);脂类(Lipids);小鼠, 近交C57BL(Mice, Inbred C57BL);哺乳动物(Mammals)
DOI
10.1002/jcp.30873
PMID
36087347
发布时间
2022-12-09
- 浏览0

Journal of cellular physiology
4226-4237页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文