首页> Frontiers in oncology> DNA damage response and repair genes in advanced bone and soft tissue sarcomas: An 8-gene signature as a candidate predictive biomarker of response to trabectedin and olaparib combination.

DNA damage response and repair genes in advanced bone and soft tissue sarcomas: An 8-gene signature as a candidate predictive biomarker of response to trabectedin and olaparib combination.

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第一作者： Alessandra,Merlini

第一单位： Candiolo Cancer Institute, FPO-IRCCS, Turin, Italy.;Department of Oncology, University of Torino, Turin, Italy.

作者： Alessandra,Merlini ^[1] ; Maria Laura,Centomo ^[1] ; Giulio,Ferrero ^[2] ; Giulia,Chiabotto ^[3] ; Umberto,Miglio ^[4] ; Enrico,Berrino ^[5] ; Giorgia,Giordano ^[1] ; Silvia,Brusco ^[1] ; Alberto,Pisacane ^[4] ; Elena,Maldi ^[4] ; Ivana,Sarotto ^[4] ; Federica,Capozzi ^[4] ; Cristina,Lano ^[1] ; Claudio,Isella ^[1] ; Giovanni,Crisafulli ^[1] ; Massimo,Aglietta ^[1] ; Angelo Paolo,Dei Tos ^[6] ; Marta,Sbaraglia ^[7] ; Dario,Sangiolo ^[1] ; Lorenzo,D'Ambrosio ^[8] ; Alberto,Bardelli ^[1] ; Ymera,Pignochino ^[9] ; Giovanni,Grignani ^[4]

作者单位： Candiolo Cancer Institute, FPO-IRCCS, Turin, Italy.;Department of Oncology, University of Torino, Turin, Italy. ^[1] Department of Clinical and Biological Sciences, University of Torino, Turin, Italy.;Department of Computer Science, University of Torino, Turin, Italy. ^[2] Department of Medical Sciences, University of Torino, Turin, Italy. ^[3] Candiolo Cancer Institute, FPO-IRCCS, Turin, Italy. ^[4] Candiolo Cancer Institute, FPO-IRCCS, Turin, Italy.;Department of Medical Sciences, University of Torino, Turin, Italy. ^[5] Department of Pathology, Azienda Ospedale-Università Padova, Padua, Italy.;Department of Medicine (DIMED), University of Padua School of Medicine, Padua, Italy. ^[6] Department of Pathology, Azienda Ospedale-Università Padova, Padua, Italy. ^[7] Candiolo Cancer Institute, FPO-IRCCS, Turin, Italy.;Department of Oncology, University of Torino, Turin, Italy.;Medical Oncology, AOU San Luigi Gonzaga, Orbassano (TO), Italy. ^[8] Candiolo Cancer Institute, FPO-IRCCS, Turin, Italy.;Department of Clinical and Biological Sciences, University of Torino, Turin, Italy. ^[9]

关键词 DNA damage response and repair genes bone and soft tissue sarcomas olaparib predictive biomarkers trabectedin

DOI 10.3389/fonc.2022.844250

PMID 36110934

发布时间 2022-09-17

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准确一般字义偏差语意偏离译文作用小提交