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Genomic signatures of selection associated with benzimidazole drug treatments in Haemonchus contortus field populations.

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第一作者： Janneke,Wit

第一单位： Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada; Host-Parasite Interactions (HPI) Program, University of Calgary, Calgary, Alberta, Canada.

作者： Janneke,Wit ^[1] ; Matthew L,Workentine ^[2] ; Elizabeth,Redman ^[2] ; Roz,Laing ^[3] ; Lewis,Stevens ^[4] ; James A,Cotton ^[5] ; Umer,Chaudhry ^[6] ; Qasim,Ali ^[7] ; Erik C,Andersen ^[8] ; Samuel,Yeaman ^[9] ; James D,Wasmuth ^[1] ; John S,Gilleard ^[10]

作者单位： Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada; Host-Parasite Interactions (HPI) Program, University of Calgary, Calgary, Alberta, Canada. ^[1] Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada. ^[2] Institute of Biodiversity Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Garscube Campus, Glasgow, UK. ^[3] Tree of Life, Wellcome Sanger Institute, Cambridge, UK. ^[4] Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, UK. ^[5] University of Edinburgh, Roslin Institute, Easter Bush Veterinary Centre, Roslin, Midlothian, UK. ^[6] Department of Parasitology FVAS, University of Agriculture, D.I. Khan, Pakistan. ^[7] Molecular Biosciences, Northwestern University, Evanston, IL, USA. ^[8] Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada. ^[9] Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada; Host-Parasite Interactions (HPI) Program, University of Calgary, Calgary, Alberta, Canada. Electronic address: jsgillea@ucalgary.ca. ^[10]

关键词 Anthelmintics Gastrointestinal nematode Isotype-1 beta-tubulin RAD-seq Resistance Selection signatures