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Thyroid cancer harboring PTEN and TP53 mutations: A peculiar molecular and clinical case report.

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第一作者： Carla,Colombo

第一单位： Division of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy.;Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.

作者： Carla,Colombo ^[1] ; Gabriele,Pogliaghi ^[2] ; Delfina,Tosi ^[3] ; Marina,Muzza ^[4] ; Gaetano,Bulfamante ^[3] ; Luca,Persani ^[5] ; Laura,Fugazzola ^[1] ; Valentina,Cirello ^[2]

作者单位： Division of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy.;Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy. ^[1] Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.;Laboratory of Endocrine and Metabolic Research, Istituto Auxologico Italiano IRCCS, Milan, Italy. ^[2] Unit of Human Pathology, Department of Health Sciences Santi Paolo e Carlo Medical School, University of Milan, Milan, Italy. ^[3] Laboratory of Endocrine and Metabolic Research, Istituto Auxologico Italiano IRCCS, Milan, Italy. ^[4] Division of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy.;Laboratory of Endocrine and Metabolic Research, Istituto Auxologico Italiano IRCCS, Milan, Italy.;Department of Biotechnology and Translational Medicine, University of Milan, Milan, Italy. ^[5]

关键词 PTEN Sorafenib TP53 aggressive follicular thyroid cancer microsatellite instability mismatch repair proteins tyrosine kinase inhibitor

DOI 10.3389/fonc.2022.949098

PMID 36119511

发布时间 2022-09-20

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