换一批One-year longitudinal association between changes in dietary choline or betaine intake and cardiometabolic variables in the PREvención con DIeta MEDiterránea-Plus (PREDIMED-Plus) trial.
第一作者：
Laura,Díez-Ricote
第一单位：
Nutritional Control of the Epigenome Group, Precision Nutrition and Obesity Program, IMDEA Food, CEI UAM + CSIC, Madrid, Spain.
作者：
Laura,Díez-Ricote [1]
;
Rodrigo,San-Cristobal [2]
;
M José,Concejo [3]
;
Miguel Á,Martínez-González [4]
;
Dolores,Corella [5]
;
Jordi,Salas-Salvadó [6]
;
Albert,Goday [7]
;
J Alfredo,Martínez [8]
;
Ángel M,Alonso-Gómez [9]
;
Julia,Wärnberg [10]
;
Jesús,Vioque [11]
;
Dora,Romaguera [12]
;
José,López-Miranda [13]
;
Ramon,Estruch [14]
;
Francisco J,Tinahones [15]
;
José,Lapetra [16]
;
Lluís,Serra-Majem [17]
;
Aurora,Bueno-Cavanillas [18]
;
Josep A,Tur [19]
;
Vicente,Martín Sánchez [20]
;
Xavier,Pintó [21]
;
José J,Gaforio [22]
;
Pilar,Matía-Martín [23]
;
Josep,Vidal [24]
;
Sebastián,Mas Fontao [25]
;
Emilio,Ros [26]
;
Zenaida,Vázquez-Ruiz [27]
;
Carolina,Ortega-Azorín [5]
;
Jesús F,García-Gavilán [28]
;
Mireia,Malcampo [29]
;
Diego,Martínez-Urbistondo [30]
;
Lucas,Tojal-Sierra [31]
;
Antonio,García Rodríguez [32]
;
Nuria,Gómez-Bellvert [33]
;
Alice,Chaplin [12]
;
Antonio,García-Ríos [34]
;
Rosa M,Bernal-López [15]
;
José M,Santos-Lozano [16]
;
Javier,Basterra-Gortari [27]
;
José V,Sorlí [5]
;
Michelle,Murphy [28]
;
Griselda,Gasulla [29]
;
Víctor,Micó [2]
;
Itziar,Salaverria-Lete [9]
;
Estibaliz,Goñi Ochandorena [35]
;
Nancy,Babio [28]
;
Xavier,Herraiz [29]
;
José M,Ordovás [36]
;
Lidia,Daimiel [37]
作者单位：
Nutritional Control of the Epigenome Group, Precision Nutrition and Obesity Program, IMDEA Food, CEI UAM + CSIC, Madrid, Spain.
[1]
Cardiometabolic Health Group, Precision Nutrition and Cardiometabolic Health Program, IMDEA Food, CEI UAM + CSIC, Madrid, Spain.
[2]
Primary Care Center Ibiza, SERMAS, Madrid, Spain.
[3]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Department of Preventive Medicine and Public Health, Navarra Institute of Health Research (IdISNA), University of Navarra, Pamplona, Spain.;Department of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA.
[4]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Department of Preventive Medicine, University of Valencia, Valencia, Spain.
[5]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Universitat Rovira i Virgili, Departament of Biochemistry and Biotechnology, Human Nutrition Unit, Reus, Spain.;Institut d'Investigació Sanitària Pere Virgili (IISPV), Reus, Spain.;Nutrition Unit, University Hospital of Sant Joan de Reus, Reus, Spain.;Unit of Preventive Medicine & Public Health, Faculty of Medicine & Health Sciences, Universitat Rovira i Virgili, Reus, Spain.
[6]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Unit of Cardiovascular Risk and Nutrition, Institut Hospital del Mar d`Investigació Médica (IMIM), Barcelona, Spain.;Department of Medicine, Universitat Autonoma de Barcelona, Barcelona, Spain.
[7]
Cardiometabolic Health Group, Precision Nutrition and Cardiometabolic Health Program, IMDEA Food, CEI UAM + CSIC, Madrid, Spain.;Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Center for Nutrition Research, Department of Nutrition, Food Sciences, and Physiology, University of Navarra, Pamplona, Spain.
[8]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Cardiovascular, Respiratory and Metabolic Area, Bioaraba Health Research Institute; Araba University Hospital, Osakidetza Basque Health Service; University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain.
[9]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Department of Nursing, University of Málaga, Institute of Biomedical Research in Malaga (IBIMA), Málaga, Spain.
[10]
CIBER de Epidemiología y Salud Pública (CIBERESP), Carlos III Institute of Health (ISCIII), Madrid, Spain.;Institute of Health and Biomedical Research of Alicante, Miguel Hernández University (ISABIAL-UMH), Alicante, Spain.
[11]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Research Group on Nutritional Epidemiology & Cardiovascular Physiopathology, Health Research Institute of the Balearic Islands (IdISBa), Palma de Mallorca, Spain.
[12]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Department of Internal Medicine, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, Cordoba, Spain.
[13]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Department of Internal Medicine, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Hospital Clinic, University of Barcelona, Barcelona, Spain.
[14]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Department of Endocrinology, Virgen de la Victoria Hospital, Málaga Biomedical Research Institute (IBIMA), University of Málaga, Málaga, Spain.
[15]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Research Unit, Department of Family Medicine, Sevilla Primary Care Health District, Sevilla, Spain.
[16]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria and Maternal and Child Insular University Hospital Center (CHUIMI), Canarian Health Service, Las Palmas de Gran Canaria, Spain.
[17]
CIBER de Epidemiología y Salud Pública (CIBERESP), Carlos III Institute of Health (ISCIII), Madrid, Spain.;Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain.
[18]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Research Group on Community Nutrition & Oxidative Stress, University of the Balearic Islands, Palma de Mallorca, Spain.
[19]
CIBER de Epidemiología y Salud Pública (CIBERESP), Carlos III Institute of Health (ISCIII), Madrid, Spain.;Institute of Biomedicine (IBIOMED), University of León, León, Spain.
[20]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Lipids and Vascular Risk Unit, Internal Medicine, Bellvitge University Hospital, Barcelona, Spain.
[21]
CIBER de Epidemiología y Salud Pública (CIBERESP), Carlos III Institute of Health (ISCIII), Madrid, Spain.;Department of Health Sciences, University Institute for Research on Olives and Olive Oils, University of Jaén, Jaén, Spain.
[22]
Department of Endocrinology and Nutrition, San Carlos Clinical Hospital Institute of Health Research (IdISSC), Madrid, Spain.
[23]
CIBER Diabetes y Enfermedades Metabólicas (CIBERDEM), Carlos III Institute of Health (ISCIII), Madrid, Spain.;Department of Endocrinology, Institut d` Investigacions Biomédiques August Pi Sunyer (IDIBAPS), Hospital Clinic, University of Barcelona, Barcelona, Spain.
[24]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Department of Endocrinology and Nutrition, Jimenez Díaz Foundation Hospital Biomedical Research Institute (IISFJD), Autonomous University of Madrid, Madrid, Spain.
[25]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Lipid Clinic, Department of Endocrinology and Nutrition, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Hospital Clínic, Barcelona, Spain.
[26]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Department of Preventive Medicine and Public Health, Navarra Institute of Health Research (IdISNA), University of Navarra, Pamplona, Spain.;Endocrinology Service, Navarra Hospital Complex, Osasunbidea, Navarro Health Service, Pamplona, Spain.
[27]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Universitat Rovira i Virgili, Departament of Biochemistry and Biotechnology, Human Nutrition Unit, Reus, Spain.;Institut d'Investigació Sanitària Pere Virgili (IISPV), Reus, Spain.;Nutrition Unit, University Hospital of Sant Joan de Reus, Reus, Spain.
[28]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Unit of Cardiovascular Risk and Nutrition, Institut Hospital del Mar d`Investigació Médica (IMIM), Barcelona, Spain.
[29]
Internal Medicine Department, HM Sanchinarro Hospital, HM Hospitals, Madrid, Spain.
[30]
Cardiovascular, Respiratory and Metabolic Area, Bioaraba Health Research Institute; Araba University Hospital, Osakidetza Basque Health Service; University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain.
[31]
Division of Preventive Medicine and Public Health, University of Malaga, Institute of Biomedical Research in Málaga (IBIMA-University of Malaga), Málaga, Spain.
[32]
San Vicent del Raspeig Health Center, Alicante, Spain.
[33]
Department of Internal Medicine, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, Cordoba, Spain.
[34]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Department of Preventive Medicine and Public Health, Navarra Institute of Health Research (IdISNA), University of Navarra, Pamplona, Spain.
[35]
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.;Nutritional Genomics and Epigenomics Group, Precision Nutrition and Obesity Program, IMDEA Food, CEI UAM + CSIC, Madrid, Spain.;Nutrition and Genomics Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA.
[36]
Nutritional Control of the Epigenome Group, Precision Nutrition and Obesity Program, IMDEA Food, CEI UAM + CSIC, Madrid, Spain.;Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, Spain.
[37]
医学主题词
老年人(Aged);女(雌)性(Female);人类(Humans);男(雄)性(Male);中年人(Middle Aged);甜菜碱(Betaine);心血管疾病(Cardiovascular Diseases);胆碱(Choline);膳食, 地中海(Diet, Mediterranean);危险因素(Risk Factors)
DOI
10.1093/ajcn/nqac255
PMID
36124652
发布时间
2024-09-09
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The American journal of clinical nutrition
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