首页> Stem cells (Dayton, Ohio)> Inhibition of O-GlcNAcase Inhibits Hematopoietic and Leukemic Stem Cell Self-Renewal and Drives Dendritic Cell Differentiation via STAT3/5 Signaling.

Inhibition of O-GlcNAcase Inhibits Hematopoietic and Leukemic Stem Cell Self-Renewal and Drives Dendritic Cell Differentiation via STAT3/5 Signaling.

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第一作者： Sudjit,Luanpitpong

第一单位： Siriraj Center of Excellence for Stem Cell Research, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

作者： Sudjit,Luanpitpong ^[1] ; Napachai,Rodboon ^[1] ; Parinya,Samart ^[1] ; Montira,Janan ^[1] ; Phatchanat,Klaihmon ^[1] ; Chanchao,Lorthongpanich ^[1] ; Yaowalak,U-Pratya ^[2] ; Surapol,Issaragrisil ^[3]

作者单位： Siriraj Center of Excellence for Stem Cell Research, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. ^[1] Division of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. ^[2] Siriraj Center of Excellence for Stem Cell Research, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.;Division of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.;Bangkok Hematology Center, Wattanosoth Hospital, BDMS Center of Excellence for Cancer, Bangkok, Thailand. ^[3]

关键词 O-GlcNAcylation acute myeloid leukemia dendritic cell differentiation therapy hematopoiesis hematopoietic stem cells leukemic stem cells macrophage myeloid differentiation

医学主题词人类(Humans);抗原, CD34(Antigens, CD34);细胞分化(Cell Differentiation);造血干细胞(Hematopoietic Stem Cells);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);STAT3转录因子(STAT3 Transcription Factor);STAT5转录因子(STAT5 Transcription Factor)

DOI 10.1093/stmcls/sxac068

PMID 36124999

发布时间 2023-02-07

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