首页> Acta pharmacologica Sinica> Upregulation of dynorphin/kappa opioid receptor system in the dorsal hippocampus contributes to morphine withdrawal-induced place aversion.

Upregulation of dynorphin/kappa opioid receptor system in the dorsal hippocampus contributes to morphine withdrawal-induced place aversion.

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第一作者： Yan,Chen

第一单位： Department of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.

作者： Yan,Chen ^[1] ; Chen-Yao,Wang ^[2] ; Gui-Ying,Zan ^[3] ; Song-Yu,Yao ^[4] ; Ying-Zhi,Deng ^[3] ; Xue-Lian,Shu ^[2] ; Wei-Wei,Wu ^[3] ; Yan,Ma ^[3] ; Yu-Jun,Wang ^[5] ; Chang-Xi,Yu ^[6] ; Jing-Gen,Liu ^[3]

作者单位： Department of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China. ^[1] CAS Key Laboratory of Receptor Research and State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Shanghai, 201203, China.;University of Chinese Academy of Sciences, No. 19 A Yuquan Road, Beijing, 100049, China. ^[2] CAS Key Laboratory of Receptor Research and State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Shanghai, 201203, China. ^[3] School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, 210023, China. ^[4] CAS Key Laboratory of Receptor Research and State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 555 Zuchongzhi Road, Shanghai, 201203, China. yjwang@simm.ac.cn. ^[5] Department of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China. changxiyu@mail.fjmu.edu.cn. ^[6]

关键词 conditioned place aversion dorsal hippocampus kappa opioid receptor morphine withdrawal norBNI p38 MAPK