换一批
换一批Treatment time and circadian genotype interact to influence radiotherapy side-effects. A prospective European validation study using the REQUITE cohort.
作者：
Adam J,Webb [1]
;
Emily,Harper [1]
;
Tim,Rattay [2]
;
Miguel E,Aguado-Barrera [3]
;
David,Azria [4]
;
Celine,Bourgier [4]
;
Muriel,Brengues [5]
;
Erik,Briers [6]
;
Renée,Bultijnck [7]
;
Jenny,Chang-Claude [8]
;
Ananya,Choudhury [9]
;
Alessandro,Cicchetti [10]
;
Dirk,De Ruysscher [11]
;
Maria Carmen,De Santis [12]
;
Alison M,Dunning [13]
;
Rebecca M,Elliott [9]
;
Laura,Fachal [14]
;
Antonio,Gómez-Caamaño [15]
;
Sara,Gutiérrez-Enríquez [16]
;
Kerstie,Johnson [2]
;
Ramón,Lobato-Busto [17]
;
Sarah L,Kerns [18]
;
Giselle,Post [7]
;
Tiziana,Rancati [10]
;
Victoria,Reyes [19]
;
Barry S,Rosenstein [20]
;
Petra,Seibold [8]
;
Alejandro,Seoane [21]
;
Paloma,Sosa-Fajardo [15]
;
Elena,Sperk [22]
;
Begoña,Taboada-Valladares [15]
;
Riccardo,Valdagni [23]
;
Ana,Vega [24]
;
Liv,Veldeman [25]
;
Tim,Ward [26]
;
Catharine M,West [9]
;
R Paul,Symonds [2]
;
Christopher J,Talbot [27]
;
REQUITE Consortium
作者单位：
Department of Genetics and Genome Biology, University of Leicester, Leicester, UK.
[1]
Leicester Cancer Research Centre, University of Leicester, Leicester, UK.
[2]
Fundación Pública Galega Medicina Xenómica, Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela, Spain.
[3]
Department of Radiation Oncology, Montpellier Cancer Institute, Université Montpellier, Inserm U1194, Montpellier, France.
[4]
Institut de Recherche en Cancérologie de Montpellier, Université Montpellier, Inserm U1194, Montpellier, France.
[5]
Patient advocate, Hasselt, Belgium.
[6]
Department of Human Structure and Repair, Ghent University, Ghent, Belgium.
[7]
Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
[8]
Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie Hospital, Manchester, UK.
[9]
Prostate Cancer Program, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
[10]
Maastricht University Medical Center, Department of Radiation Oncology (Maastro clinic), GROW School for Oncology and Developmental Biology, Maastricht, the Netherlands.
[11]
Department of Radiation Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
[12]
Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
[13]
Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.
[14]
Instituto de Investigación Sanitaria de Santiago de Compostela, Spain; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.
[15]
Hereditary Cancer Genetics Group, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
[16]
Department of Medical Physics, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.
[17]
Departments of Radiation Oncology and Surgery, University of Rochester Medical Center, Rochester, New York, NY, United States.
[18]
Radiation Oncology Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
[19]
Department of Radiation Oncology, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, USA.
[20]
Medical Physics Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
[21]
Department of Radiation Oncology, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
[22]
Prostate Cancer Program, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Department of Radiation Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Department of Oncology and Haematology-Oncology, Universita degli Studi di Milano, Italy.
[23]
Fundación Pública Galega Medicina Xenómica, Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela, Spain; Biomedical Network on Rare Diseases (CIBERER), Spain.
[24]
Department of Human Structure and Repair, Ghent University, Ghent, Belgium; Department of Radiation Oncology, Ghent University Hospital, Ghent, Belgium.
[25]
Patient advocate, NCRI CTRad consumer, UK.
[26]
Leicester Cancer Research Centre, University of Leicester, Leicester, UK. Electronic address: cjt14@le.ac.uk.
[27]
主题词
萎缩(Atrophy);昼夜节律(Circadian Rhythm);基因型(Genotype);人类(Humans);周期昼夜节律蛋白质类(Period Circadian Proteins);前瞻性研究(Prospective Studies);辐射损伤(Radiation Injuries);ras蛋白质类(ras Proteins)
DOI
10.1016/j.ebiom.2022.104269
PMID
36130474
发布时间
2024-02-14
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EBioMedicine
2022年84卷
104269页
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