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SMN controls neuromuscular junction integrity through U7 snRNP.

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第一作者： Sarah,Tisdale

第一单位： Center for Motor Neuron Biology and Disease, Columbia University, New York, NY 10032, USA; Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA; Department of Neurology, Columbia University, New York, NY 10032, USA.

作者： Sarah,Tisdale ^[1] ; Meaghan,Van Alstyne ^[1] ; Christian M,Simon ^[2] ; George Z,Mentis ^[1] ; Livio,Pellizzoni ^[3]

作者单位： Center for Motor Neuron Biology and Disease, Columbia University, New York, NY 10032, USA; Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA; Department of Neurology, Columbia University, New York, NY 10032, USA. ^[1] Center for Motor Neuron Biology and Disease, Columbia University, New York, NY 10032, USA; Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA. ^[2] Center for Motor Neuron Biology and Disease, Columbia University, New York, NY 10032, USA; Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA; Department of Neurology, Columbia University, New York, NY 10032, USA. Electronic address: lp2284@cumc.columbia.edu. ^[3]

关键词 3′-end mRNA processing CP: Neuroscience Lsm proteins RNP assembly U7 small nuclear ribonucleoprotein (snRNP)histone gene regulation motor neurons neurodegeneration neuromuscular junction (NMJ)spinal muscular atrophy (SMA)survival motor neuron (SMN)