A Combination of Genome Mining with an OSMAC Approach Facilitates the Discovery of and Contributions to the Biosynthesis of Melleolides from the Basidiomycete <i>Armillaria tabescens</i>.

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作者： Tao,Zhang ^[1] ; Guowei,Cai ^[1] ; Xiaoting,Rong ^[2] ; Yuquan,Wang ^[1] ; KaiKai,Gong ^[3] ; Wancang,Liu ^[1] ; Lu,Wang ^[2] ; Xu,Pang ^[1] ; Liyan,Yu ^[1]

作者单位： Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China. ^[1] Medical Research Center, Binzhou Medical University Hospital, Binzhou, Shandong 256603, China. ^[2] College of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu 212003, China. ^[3]

关键词 Armillaria tabescens OSMAC strategy genome mining melleolides transcriptome

主题词蜜环菌属(Armillaria);担子菌纲(Basidiomycota);内酰胺类(Lactams);多基因族(Multigene Family);RNA(RNA)

DOI 10.1021/acs.jafc.2c04079

PMID 36134616

发布时间 2022-10-06

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