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Development and Characterization of Type I, Type II, and Type III LIM-Kinase Chemical Probes.

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第一作者： Thomas,Hanke

第一单位： Institute for Pharmaceutical Chemistry, Johann Wolfgang Goethe-University, Max-von-Laue-Str. 9, D-60438 Frankfurt am Main, Germany.;Structural Genomics Consortium (SGC), Buchmann Institute for Molecular Life Sciences, Johann Wolfgang Goethe-University, Max-von-Laue-Str. 15, D-60438 Frankfurt am Main, Germany.

作者： Thomas,Hanke ^[1] ; Sebastian,Mathea ^[1] ; Julia,Woortman ^[2] ; Eidarus,Salah ^[3] ; Benedict-Tilman,Berger ^[1] ; Anthony,Tumber ^[3] ; Risa,Kashima ^[4] ; Akiko,Hata ^[4] ; Bernhard,Kuster ^[5] ; Susanne,Müller ^[1] ; Stefan,Knapp ^[6]

作者单位： Institute for Pharmaceutical Chemistry, Johann Wolfgang Goethe-University, Max-von-Laue-Str. 9, D-60438 Frankfurt am Main, Germany.;Structural Genomics Consortium (SGC), Buchmann Institute for Molecular Life Sciences, Johann Wolfgang Goethe-University, Max-von-Laue-Str. 15, D-60438 Frankfurt am Main, Germany. ^[1] Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), D-85354 Freising, Germany. ^[2] Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom. ^[3] Cardiovascular Research Institute, University of California, San Francisco, San Francisco, California 94143, United States. ^[4] Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), D-85354 Freising, Germany.;German Translational Cancer Network (DKTK), Site Frankfurt/Mainz, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany. ^[5] Institute for Pharmaceutical Chemistry, Johann Wolfgang Goethe-University, Max-von-Laue-Str. 9, D-60438 Frankfurt am Main, Germany.;Structural Genomics Consortium (SGC), Buchmann Institute for Molecular Life Sciences, Johann Wolfgang Goethe-University, Max-von-Laue-Str. 15, D-60438 Frankfurt am Main, Germany.;German Translational Cancer Network (DKTK), Site Frankfurt/Mainz, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany. ^[6]

医学主题词肌动蛋白类(Actins);Lim激酶类(Lim Kinases);分子探针(Molecular Probes)

DOI 10.1021/acs.jmedchem.2c01106

PMID 36136092

发布时间 2022-11-20

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准确一般字义偏差语意偏离译文作用小提交