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首页> Biomaterials> Tumor oxygenation nanoliposome synergistic hypoxia-inducible-factor-1 inhibitor enhanced Iodine-125 seed brachytherapy for esophageal cancer.

Tumor oxygenation nanoliposome synergistic hypoxia-inducible-factor-1 inhibitor enhanced Iodine-125 seed brachytherapy for esophageal cancer.

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作者： Xijuan,Yao ^[1] ; Shuting,Lu ^[1] ; Cheng,Feng ^[1] ; Ruiyang,Suo ^[2] ; Hang,Li ^[1] ; Yi,Zhang ^[3] ; Qi,Chen ^[1] ; Jian,Lu ^[4] ; Bo,Wu ^[5] ; Jinhe,Guo ^[6]

作者单位： Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, 210009, PR China. ^[1] Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, PR China. ^[2] School of Medicine, Southeast University, Nanjing, 210009, PR China. ^[3] Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, 210009, PR China. Electronic address: lujian43307131@126.com. ^[4] Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, PR China. Electronic address: wubo5317@whu.edu.cn. ^[5] Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, 210009, PR China. Electronic address: jinheguo@sina.com. ^[6]

关键词 (125)I brachytherapy Esophageal cancer HIF-1 functional inhibition Radiosensitizer Tumor hypoxia

主题词吖啶黄(Acriflavine);近距离放射疗法(Brachytherapy);过氧化氢酶(Catalase);细胞系, 肿瘤(Cell Line, Tumor);食管肿瘤(Esophageal Neoplasms);人类(Humans);过氧化氢(Hydrogen Peroxide);缺氧诱导因子1(Hypoxia-Inducible Factor 1);缺氧诱导因子1, α亚基(Hypoxia-Inducible Factor 1, alpha Subunit);碘放射性同位素(Iodine Radioisotopes);脂质体(Liposomes);基质金属蛋白酶2(Matrix Metalloproteinase 2);氧(Oxygen);血管内皮生长因子A(Vascular Endothelial Growth Factor A)

DOI 10.1016/j.biomaterials.2022.121801

PMID 36137416

发布时间 2022-12-22

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Biomaterials

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