Ameliorative Effect of Dabigatran on CFA-Induced Rheumatoid Arthritis via Modulating Kallikrein-Kinin System in Rats.

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作者： Mahmoud E,Youssef ^[1] ; Mustafa A,Abdel-Reheim ^[2] ; Mohamed A,Morsy ^[3] ; Mahmoud,El-Daly ^[4] ; Gamal M K,Atwa ^[5] ; Galal,Yahya ^[6] ; Simona,Cavalu ^[7] ; Sameh,Saber ^[8] ; Ahmed Gaafar,Ahmed Gaafar ^[1]

作者单位： Department of Pharmacology and Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa 11152, Egypt. ^[1] Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Beni Suef 62521, Egypt. ^[2] Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia. ^[3] Department of Pharmacology, Faculty of Medicine, Minia University, El-Minia 61511, Egypt. ^[4] Department of Pharmacology and Toxicology, Faculty of Pharmacy, Minia University, El-Minia 61519, Egypt. ^[5] Department of Biochemistry, Faculty of Pharmacy, Port Said University, Port Said 42515, Egypt. ^[6] Department of Microbiology and Immunology, Faculty of Pharmacy, Zagazig University, Al Sharqia 44519, Egypt. ^[7] Faculty of Medicine and Pharmacy, University of Oradea, P-ta 1 Decembrie 10, 410087 Oradea, Romania. ^[8] Department of Pharmacology and Toxicology, Faculty of Pharmacy, Port Said University, Port Said 42511, Egypt. ^[9]

关键词 ACPA Bradykinin Kallikrein-Kinin system RANKL dabigatran rheumatoid arthritis