第一作者:
Roni F,Kunst
第一单位:
Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.;Amsterdam Gastroenterology, Endocrinology and Metabolism (AGEM), Amsterdam University Medical Centers, The Netherlands.
作者:
关键词
ALT, alanine transaminaseASBT, apical sodium-dependent bile acid transporterASBTi, ASBT inhibitorsAST, aspartate transaminaseAlagilleApical sodium-dependent bile acid transporter (ASBT)BDL, bile duct ligationBSEPBile salt pool sizeCCl4, carbon tetrachlorideCK7, cytokeratin 7CholestasisFRET, F?rster resonance energy transferG-OCA, glycine-conjugated OCAHepG2 cell, hepatocarcinoma cellIBATMDR2, multidrug resistance protein 2NASH, non-alcoholic steatohepatitisNGM282, non-tumorigenic fibroblast growth factor 19 analogueNTCPNTCP, Na+/taurocholate cotransporting polypeptideNucleoBAS, nuclear Bile Acid SensorOCA, obeticholic acidPBC, primary biliary cholangitisPFICPentaOH, pentahydroxylatedRT-qPCR, real-time quantitative PCRRenal excretionT-OCA, taurine-conjugated OCATCA, taurocholic acidTetraOH, tetrahydroxylatedU2OS, osteosarcoma cellUHPLC-MS, ultrahigh-performance liquid chromatography mass spectrometryWT, wild-type
DOI
10.1016/j.jhepr.2022.100573
PMID
36160754
发布时间
2025-05-30
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JHEP reports
2022年4卷11期
100573页
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