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Exploratory genomic analysis of high-grade neuroendocrine neoplasms across diverse primary sites.

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第一作者： Thomas Yang,Sun

第一单位： Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.

作者： Thomas Yang,Sun ^[1] ; Lan,Zhao ^[1] ; Paul,Van Hummelen ^[1] ; Brock,Martin ^[2] ; Kathleen,Hornbacker ^[3] ; HoJoon,Lee ^[1] ; Li C,Xia ^[4] ; Sukhmani K,Padda ^[5] ; Hanlee P,Ji ^[6] ; Pamela,Kunz ^[7]

作者单位： Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA. ^[1] Department of Pathology, Stanford University School of Medicine, Stanford, California, USA. ^[2] Clinical Trials Office, Stanford University, Stanford, California, USA. ^[3] Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.;Division of Biostatistics, Department of Epidemiology and Public Health, Albert Einstein College of Medicine, Bronx, New York, USA. ^[4] Cedars-Sinai Medical Center, Department of Medical Oncology, Los Angeles, California, USA. ^[5] Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.;Stanford Genome Technology Center, Stanford, California, USA. ^[6] Yale School of Medicine, Smilow Cancer Hospital, Yale Cancer Center, New Haven, Connecticut, USA. ^[7]

关键词 APC CDK4 CDKN2A RB1 TP53 cell cycling genomics grade 3 high grade neuroendocrine carcinoma neuroendocrine neoplasm neuroendocrine tumor sequencing tumor mutation burden

医学主题词人类(Humans);胃肿瘤(Stomach Neoplasms);神经内分泌瘤(Neuroendocrine Tumors);预后(Prognosis);基因组学(Genomics);突变(Mutation);胰腺肿瘤(Pancreatic Neoplasms);肠肿瘤(Intestinal Neoplasms)

DOI 10.1530/ERC-22-0015

PMID 36165930

发布时间 2023-11-05

基金项目

P30 CA124435/CA/NCI NIH HHS/United States U54 CA261717/CA/NCI NIH HHS/United States UL1 RR025744/RR/NCRR NIH HHS/United States UL1 TR003142/TR/NCATS NIH HHS/United States

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