<i>FOXO3</i> mutation predicting gefitinib-induced hepatotoxicity in NSCLC patients through regulation of autophagy.

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作者： Shaoxing,Guan ^[1] ; Xi,Chen ^[2] ; Youhao,Chen ^[1] ; Guohui,Wan ^[1] ; Qibiao,Su ^[3] ; Heng,Liang ^[1] ; Yunpeng,Yang ^[2] ; Wenfeng,Fang ^[2] ; Yan,Huang ^[2] ; Hongyun,Zhao ^[2] ; Wei,Zhuang ^[4] ; Shu,Liu ^[1] ; Fei,Wang ^[2] ; Wei,Feng ^[5] ; Xiaoxu,Zhang ^[1] ; Min,Huang ^[1] ; Xueding,Wang ^[1] ; Li,Zhang ^[1]

作者单位： Laboratory of Drug Metabolism and Pharmacokinetics, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510060, China. ^[1] State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China. ^[2] College of Health Science, Guangdong Pharmaceutical University, Guangzhou 510006, China. ^[3] Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510080, China. ^[4] Ersha Department of Pharmacy, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510105, China. ^[5]

关键词 Autophagy FOXO3 Gefitinib Hepatotoxicity Pharmacogenomics Pharmacokinetics Pharmacometabolomic

DOI 10.1016/j.apsb.2022.02.006

PMID 36176901

发布时间 2022-10-01

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Acta pharmaceutica Sinica. B

2022年12卷9期

3639-3649页

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<i>FOXO3</i> mutation predicting gefitinib-induced hepatotoxicity in NSCLC patients through regulation of autophagy.

Acta pharmaceutica Sinica. B

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Acta pharmaceutica Sinica. B

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<i>FOXO3</i> mutation predicting gefitinib-induced hepatotoxicity in NSCLC patients through regulation of autophagy.

Acta pharmaceutica Sinica. B

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Acta pharmaceutica Sinica. B

相关期刊

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