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SARS-CoV-2 Nsp14 protein associates with IMPDH2 and activates NF-κB signaling.

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第一作者： Tai-Wei,Li

第一单位： Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH, United States.

作者： Tai-Wei,Li ^[1] ; Adam D,Kenney ^[2] ; Jun-Gyu,Park ^[3] ; Guillaume N,Fiches ^[1] ; Helu,Liu ^[4] ; Dawei,Zhou ^[1] ; Ayan,Biswas ^[5] ; Weiqiang,Zhao ^[1] ; Jianwen,Que ^[4] ; Netty,Santoso ^[1] ; Luis,Martinez-Sobrido ^[3] ; Jacob S,Yount ^[2] ; Jian,Zhu ^[6]

作者单位： Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH, United States. ^[1] Department of Microbial Infection and Immunity, The Ohio State University Wexner Medical Center, Columbus, OH, United States. ^[2] Texas Biomedical Research Institute, San Antonio, TX, United States. ^[3] Department of Medicine, Columbia University Medical Center, New York, NY, United States. ^[4] Department of Genetics, The University of Alabama at Birmingham, Birmingham, AL, United States. ^[5] Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH, United States.;Department of Microbial Infection and Immunity, The Ohio State University Wexner Medical Center, Columbus, OH, United States. ^[6]

关键词 IL-8 IMPDH2 NF-κB Nsp14 SARS-CoV-2 mycophenolic acid ribavirin